WormBase Tree Display for Gene: WBGene00003638
expand all nodes | collapse all nodes | view schema
WBGene00003638 | Evidence | Paper_evidence | WBPaper00003416 | ||||
---|---|---|---|---|---|---|---|
WBPaper00004181 | |||||||
SMap | S_parent | Sequence | ZK662 | ||||
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | nhr | ||||||
Allele (172) | |||||||
Strain | WBStrain00000017 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (14) | |||||||
Ortholog (37) | |||||||
Paralog (217) | |||||||
Structured_description | Concise_description | nhr-48 encodes a nuclear receptor that, along with daf-12 and nhr-8, comprise the C. elegans members of a conserved nuclear receptor subfamily that includes Drosophila HR96 and the vertebrate vitamin D, PXR, and CAR proteins; an nhr-48::gfp reporter is expressed in the pharyngeal gland in larvae and adults and in the spermatheca beginning in L4; weak hypodermal expression is also seen in some transgenic lines. | Paper_evidence | WBPaper00004181 | |||
WBPaper00006412 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 17 May 2007 00:00:00 | ||||||
Automated_description | Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including anterior gonad arm; pharyngeal gland cell; and spermatheca. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); autosomal recessive limb-girdle muscular dystrophy type 2B; carcinoma (multiple); and lung disease (multiple). Is an ortholog of human VDR (vitamin D receptor). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model (53) | ||||||
Molecular_info | Corresponding_CDS | ZK662.3a | |||||
ZK662.3b | |||||||
ZK662.3c | |||||||
ZK662.3d | |||||||
Corresponding_CDS_history | ZK662.3:wp80 | ||||||
ZK662.3a:wp272 | |||||||
ZK662.3b:wp272 | |||||||
Corresponding_transcript | ZK662.3a.1 | ||||||
ZK662.3b.1 | |||||||
ZK662.3c.1 | |||||||
ZK662.3d.1 | |||||||
Other_sequence | ACC30960_1 | ||||||
EY465586.1 | |||||||
AS13263 | |||||||
CBC16456_1 | |||||||
JI166537.1 | |||||||
CRC04316_1 | |||||||
AE01982 | |||||||
JI221228.1 | |||||||
CR00423 | |||||||
Associated_feature (25) | |||||||
Transcription_factor | WBTranscriptionFactor000408 | ||||||
Experimental_info | RNAi_result | WBRNAi00059624 | Inferred_automatically | RNAi_primary | |||
WBRNAi00063664 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00063665 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr2867 | ||||||
Expr13121 | |||||||
Expr14786 | |||||||
Expr1027283 | |||||||
Expr1031682 | |||||||
Expr1163029 | |||||||
Expr2014197 | |||||||
Expr2032438 | |||||||
Drives_construct | WBCnstr00010997 | ||||||
WBCnstr00035978 | |||||||
Construct_product | WBCnstr00021753 | ||||||
WBCnstr00035978 | |||||||
Microarray_results (31) | |||||||
Expression_cluster (101) | |||||||
Interaction (17) | |||||||
Map_info | Map | X | Position | 22.9404 | Error | 0.00227 | |
Positive | Positive_clone | ZK662 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4383 | |||||
4524 | |||||||
Pseudo_map_position | |||||||
Reference (14) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |