WormBase Tree Display for Gene: WBGene00003889
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WBGene00003889 | SMap | S_parent | Sequence | B0212 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | osm | ||||||
Allele (120) | |||||||
Legacy_information | [C.elegansII] n1601 : defective in osmotic avoidance, also in nose touch avoidance (Not); Adp (partly defective adaptation to isoamyl alcohol and butanone); normal chemotaxis.OA5: n1516, n1603, n2473, ky10 (similar). [Colbert & Bargmann 1995; JT; KP; MT] | ||||||
Strain | WBStrain00023453 | ||||||
WBStrain00036458 | |||||||
WBStrain00005214 | |||||||
WBStrain00007483 | |||||||
WBStrain00052609 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (33) | |||||||
Ortholog (45) | |||||||
Paralog (4) | |||||||
Structured_description | Concise_description | osm-9 encodes a TRPV channel homologous to capsaicin receptors; osm-9 is involved in sensory responses to a subset of chemical stimuli and to ASH neuron-mediated osmotic and mechanical stimuli; OSM-9 is also involved in adaptation to volatile odorants and salts; OSM-9 is expressed in a variety of sensory neurons and shows neuron-specific localization to either the cell body or the cilium. | Paper_evidence | WBPaper00002166 | |||
WBPaper00002930 | |||||||
WBPaper00005150 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 20 Apr 2011 00:00:00 | ||||||
Automated_description | Enables calcium channel activity and temperature-gated cation channel activity. Involved in several processes, including heat acclimation; negative adaptation of signaling pathway; and nervous system process. Located in neuronal cell body; non-motile cilium; and perinuclear region of cytoplasm. Expressed in RIG; head mesodermal cell; rectal gland cell; sensory neurons; and uterine toroidal epithelial cell. Human ortholog(s) of this gene implicated in several diseases, including keratosis (multiple); motor neuron disease (multiple); and osteochondrodysplasia (multiple). Is an ortholog of human TRPV3 (transient receptor potential cation channel subfamily V member 3); TRPV4 (transient receptor potential cation channel subfamily V member 4); and TRPV5 (transient receptor potential cation channel subfamily V member 5). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model (17) | ||||||
Molecular_info | Corresponding_CDS | B0212.5 | |||||
Corresponding_transcript | B0212.5.1 | ||||||
Other_sequence (14) | |||||||
Associated_feature | WBsf667839 | ||||||
WBsf995982 | |||||||
Experimental_info | RNAi_result (14) | ||||||
Expr_pattern (12) | |||||||
Drives_construct | WBCnstr00000837 | ||||||
WBCnstr00005979 | |||||||
WBCnstr00008561 | |||||||
WBCnstr00010985 | |||||||
WBCnstr00010991 | |||||||
WBCnstr00011000 | |||||||
WBCnstr00011004 | |||||||
WBCnstr00012945 | |||||||
WBCnstr00023098 | |||||||
WBCnstr00035811 | |||||||
Construct_product | WBCnstr00000837 | ||||||
WBCnstr00006801 | |||||||
WBCnstr00010991 | |||||||
WBCnstr00011000 | |||||||
WBCnstr00011004 | |||||||
WBCnstr00012945 | |||||||
WBCnstr00020618 | |||||||
WBCnstr00035811 | |||||||
Regulate_expr_cluster | WBPaper00049594:osm-9(ok1677)_NaCl(200mM)_upregulate | ||||||
WBPaper00049594:osm-9(ok1677)_upregulated | |||||||
Microarray_results (18) | |||||||
Expression_cluster (103) | |||||||
Interaction (116) | |||||||
Anatomy_function | WBbtf0291 | ||||||
WBProcess | WBbiopr:00000002 | ||||||
Map_info | Map | IV | Position | -3.15659 | Error | 0.016734 | |
Well_ordered | |||||||
Positive | Positive_clone | B0212 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
CX#2-12 | |||||||
Mapping_data | 2_point | 3729 | |||||
3730 | |||||||
Multi_point | 1365 | ||||||
1366 | |||||||
Reference (225) | |||||||
Remark | Possibly homologous to mammalian capsaicin receptor VR1. Some osm-9 mutants are sensitive to capsaicin.[bionet.celegans from Olsen] | Curator_confirmed | WBPerson1250 | ||||
Method | Gene |