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WormBase Tree Display for Gene: WBGene00004038

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Name Class

WBGene00004038EvidencePerson_evidenceWBPerson51
SMapS_parentSequenceT01E8
IdentityVersion1
NameCGC_nameplc-3Person_evidenceWBPerson51
Sequence_nameT01E8.3
Molecular_nameT01E8.3
T01E8.3.1
CE42905
Other_nameCELE_T01E8.3Accession_evidenceNDBBX284602
Public_nameplc-3
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:33WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classplc
Allele (92)
StrainWBStrain00030955
RNASeq_FPKM (74)
GO_annotation (18)
Ortholog (47)
ParalogWBGene00001177Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00004036Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004037Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00004039Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00004045Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionplc-3 encodes a phospholipase C gamma homolog; PLC-3 activity is required for regulation of a number of biological processes, including ovulatory sheath contractions, nose touch, behavioral quiescence, oscillatory Ca2+ signaling in the intestine, innate immunity, and response to wounding; plc-3 reporter fusions are expressed in sheath cells and the spermatheca, the intestine, embryonic cells including the epidermal cells during morphogenesis, and the ALA neuron.Paper_evidenceWBPaper00024307
WBPaper00026831
WBPaper00031030
WBPaper00031631
WBPaper00033094
WBPaper00035170
Curator_confirmedWBPerson1843
Date_last_updated05 Jun 2013 00:00:00
Automated_descriptionPredicted to enable phosphatidylinositol phospholipase C activity. Involved in sleep. Expressed in ALA; gonad; intestine; and non-striated muscle. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; carcinoma (multiple); familial adenomatous polyposis; and familial cold autoinflammatory syndrome 3. Is an ortholog of human PLCG2 (phospholipase C gamma 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (11)
Molecular_infoCorresponding_CDST01E8.3
Corresponding_CDS_historyT01E8.3:wp193
Corresponding_transcriptT01E8.3.1
Other_sequence (29)
Associated_featureWBsf717029
WBsf717792
WBsf221986
Experimental_infoRNAi_result (39)
Expr_pattern (11)
Drives_constructWBCnstr00006967
WBCnstr00007417
WBCnstr00011072
WBCnstr00013403
WBCnstr00016246
WBCnstr00022590
WBCnstr00022592
WBCnstr00035728
Construct_productWBCnstr00011072
WBCnstr00013403
WBCnstr00022592
WBCnstr00035728
Microarray_results (24)
Expression_cluster (81)
Interaction (91)
WBProcessWBbiopr:00000010
WBbiopr:00000039
WBbiopr:00000044
Map_infoMapIIPosition2.30656Error0.010836
PositivePositive_cloneT01E8Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4856
4823
4630
4979
Pseudo_map_position
Reference (26)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene