WormBase Tree Display for Gene: WBGene00004203
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| WBGene00004203 | SMap | S_parent | Sequence | Y113G7B | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | swsn-1 | Person_evidence | WBPerson552 | |||||
| WBPerson407 | |||||||||
| Sequence_name | Y113G7B.23 | ||||||||
| Molecular_name (24) | |||||||||
| Other_name | psa-1 | Person_evidence | WBPerson552 | ||||||
| CELE_Y113G7B.23 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | swsn-1 | ||||||||
| DB_info | Database | AceView | gene | 5U710 | |||||
| WormQTL | gene | WBGene00004203 | |||||||
| WormFlux | gene | WBGene00004203 | |||||||
| NDB | locus_tag | CELE_Y113G7B.23 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004203|UniProtKB=H8ESF3 | |||||||
| family | PTHR12802 | ||||||||
| NCBI | gene | 180324 | |||||||
| RefSeq | protein | NM_001392707.1 | |||||||
| NM_001269978.4 | |||||||||
| NM_001392706.1 | |||||||||
| NM_001373203.2 | |||||||||
| NM_001269979.3 | |||||||||
| NM_001269977.5 | |||||||||
| NM_001380878.1 | |||||||||
| NM_001373205.2 | |||||||||
| TrEMBL | UniProtAcc | G5EF87 | |||||||
| A0A3P6P9B9 | |||||||||
| A0A3P6NPD2 | |||||||||
| A0A3P6NNV9 | |||||||||
| H8ESF3 | |||||||||
| H8ESF4 | |||||||||
| A0A3P6N6K6 | |||||||||
| A0A3P6MYA1 | |||||||||
| UniProt_GCRP | UniProtAcc | H8ESF3 | |||||||
| OMIM | gene | 601732 | |||||||
| 601734 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 11 Feb 2011 15:11:27 | WBPerson2970 | Name_change | CGC_name | swsn-1 | ||||
| Other_name | psa-1 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | swsn | ||||||||
| Allele (321) | |||||||||
| Strain | WBStrain00026529 | ||||||||
| WBStrain00031320 | |||||||||
| WBStrain00034620 | |||||||||
| WBStrain00008468 | |||||||||
| WBStrain00033863 | |||||||||
| WBStrain00051162 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (29) | |||||||||
| Contained_in_operon | CEOP5508 | ||||||||
| Ortholog (45) | |||||||||
| Structured_description | Concise_description | swsn-1 encodes an ortholog of SWI3, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; swsn-1 is probably required during mitosis of the T cells for asymmetric cell division, and in addition, is required for embryonic and larval development, as well as normal levels of fertility; swsn-1 exhibits strong genetic interactions with lin-35/Rb, as swsn-1 larval lethality and sterility at 20 degrees C are greatly enhanced in lin-35;swsn-1 double mutants. | Paper_evidence | WBPaper00004350 | |||||
| WBPaper00024320 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 01 Aug 2011 00:00:00 | ||||||||
| Automated_description | Enables identical protein binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of vulval development; and positive regulation of growth rate. Predicted to be part of SWI/SNF complex. Expressed in several structures, including vulval cell. Used to study alcohol use disorder and cancer. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 8; carcinoma (multiple); and hydrocephalus. Is an ortholog of human SMARCC1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1) and SMARCC2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:162 | Homo sapiens | Paper_evidence | WBPaper00060275 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 28 Jul 2022 00:00:00 | ||||||||
| DOID:1574 | Homo sapiens | Paper_evidence | WBPaper00046494 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 20 May 2019 00:00:00 | ||||||||
| Potential_model | DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11104) | |||||
| DOID:0112367 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11105) | ||||||
| DOID:4450 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11104) | ||||||
| DOID:0080199 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11104) | ||||||
| DOID:10908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11104) | ||||||
| DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11104) | ||||||
| Models_disease_in_annotation | WBDOannot00000662 | ||||||||
| WBDOannot00001296 | |||||||||
| Molecular_info | Corresponding_CDS | Y113G7B.23a | |||||||
| Y113G7B.23b | |||||||||
| Y113G7B.23c | |||||||||
| Y113G7B.23d | |||||||||
| Y113G7B.23e | |||||||||
| Y113G7B.23f | |||||||||
| Y113G7B.23g | |||||||||
| Y113G7B.23h | |||||||||
| Corresponding_transcript | Y113G7B.23a.1 | ||||||||
| Y113G7B.23b.1 | |||||||||
| Y113G7B.23c.1 | |||||||||
| Y113G7B.23d.1 | |||||||||
| Y113G7B.23e.1 | |||||||||
| Y113G7B.23f.1 | |||||||||
| Y113G7B.23g.1 | |||||||||
| Y113G7B.23h.1 | |||||||||
| Other_sequence (54) | |||||||||
| Associated_feature (16) | |||||||||
| Transcription_factor | WBTranscriptionFactor001085 | ||||||||
| Experimental_info | RNAi_result (42) | ||||||||
| Expr_pattern | Expr1079 | ||||||||
| Expr9853 | |||||||||
| Expr12993 | |||||||||
| Expr1010553 | |||||||||
| Expr1032060 | |||||||||
| Expr1158916 | |||||||||
| Expr2017156 | |||||||||
| Expr2035292 | |||||||||
| Drives_construct | WBCnstr00009747 | ||||||||
| WBCnstr00010068 | |||||||||
| WBCnstr00021725 | |||||||||
| WBCnstr00038386 | |||||||||
| Construct_product | WBCnstr00010068 | ||||||||
| WBCnstr00021725 | |||||||||
| Regulate_expr_cluster | WBPaper00060764:swsn-1(os22ts)_downregulated | ||||||||
| WBPaper00060764:swsn-1(os22ts)_upregulated | |||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (144) | |||||||||
| Interaction (327) | |||||||||
| Anatomy_function | WBbtf0750 | ||||||||
| Map_info | Map | V | Position | 24.9776 | Error | 0.002929 | |||
| Positive | Positive_clone | Y113G7B | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4265 | |||||||
| 4608 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (33) | |||||||||
| Remark | Sequence connection from [Sawa H, Kouike H, Okano H], [020621 krb] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
