WormBase Tree Display for Gene: WBGene00004308
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| WBGene00004308 | SMap | S_parent | Sequence | C25D7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | rap-2 | Person_evidence | WBPerson490 | |||||
| Sequence_name | C25D7.7 | ||||||||
| Molecular_name | C25D7.7 | ||||||||
| C25D7.7.1 | |||||||||
| CE35831 | |||||||||
| Other_name | CELE_C25D7.7 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | rap-2 | ||||||||
| DB_info | Database | AceView | gene | 5P542 | |||||
| WormQTL | gene | WBGene00004308 | |||||||
| WormFlux | gene | WBGene00004308 | |||||||
| NDB | locus_tag | CELE_C25D7.7 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004308|UniProtKB=O17599 | |||||||
| family | PTHR24070 | ||||||||
| NCBI | gene | 180011 | |||||||
| RefSeq | protein | NM_074306.3 | |||||||
| TrEMBL | UniProtAcc | O17599 | |||||||
| UniProt_GCRP | UniProtAcc | O17599 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:34 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rap | ||||||||
| Allele (44) | |||||||||
| Strain | WBStrain00035484 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (47) | |||||||||
| Paralog (14) | |||||||||
| Structured_description | Concise_description | rap-2 encodes a Ras-related GTPase that is most similar to the RAP2 members of the Ras GTPase superfamily; by homology, RAP-2 is predicted to function as a membrane-localized GTPase that likely plays a role in signal transduction; loss-of- and gain-of-functions of rap-2 causes synapse patterning defect in DA motor neurons. | Paper_evidence | WBPaper00054962 | |||||
| Person_evidence | WBPerson3718 | ||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson324 | |||||||||
| Date_last_updated | 10 Oct 2018 00:00:00 | ||||||||
| Automated_description | Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Involved in collagen and cuticulin-based cuticle development and epidermis development. Predicted to be located in plasma membrane. Expressed in DA8; DA9; and motor neurons. Is an ortholog of human RAP2A (RAP2A, member of RAS oncogene family). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C25D7.7 | |||||||
| Corresponding_CDS_history | C25D7.7:wp111 | ||||||||
| Corresponding_transcript | C25D7.7.1 | ||||||||
| Other_sequence (34) | |||||||||
| Associated_feature | WBsf669767 | ||||||||
| WBsf1002222 | |||||||||
| WBsf1002223 | |||||||||
| WBsf1020967 | |||||||||
| WBsf1020968 | |||||||||
| WBsf235022 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00107766 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00029189 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00041175 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram220 | ||||||||
| Expr5334 | |||||||||
| Expr13835 | |||||||||
| Expr1022792 | |||||||||
| Expr1032133 | |||||||||
| Expr1145207 | |||||||||
| Expr2015256 | |||||||||
| Expr2033490 | |||||||||
| Drives_construct | WBCnstr00003819 | ||||||||
| WBCnstr00035574 | |||||||||
| WBCnstr00040192 | |||||||||
| Construct_product | WBCnstr00035574 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (98) | |||||||||
| Interaction (37) | |||||||||
| Map_info | Map | V | Position | 7.25494 | Error | 0.011134 | |||
| Positive | Positive_clone | C25D7 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4623 | |||||||
| Pseudo_map_position | |||||||||
| Reference (12) | |||||||||
| Remark | rap-2 is not cgc approved -- F46B3.9 does not seem to be a rapsyn homolog, and may need a different name. F46B3.9 may have a knockout allele, ok148 (see [wm2001p920]). This allele is not currently listed by the CGC. Possible confusion with rap-1(ok145). [030108 ck1] | ||||||||
| Sequence connection was F46B3.9 | CGC_data_submission | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
