WormBase Tree Display for Gene: WBGene00004421
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| WBGene00004421 | Evidence | Accession_evidence | EMBL | AJ270980 | |||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F10B5 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | rpl-10 | |||||||
| Sequence_name | F10B5.1 | ||||||||
| Molecular_name | F10B5.1 | ||||||||
| F10B5.1.1 | |||||||||
| CE01543 | |||||||||
| Other_name | CELE_F10B5.1 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | rpl-10 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:35 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rpl | ||||||||
| Allele (14) | |||||||||
| Legacy_information | Orthologous to yeast (S.cerevisiae) ribosomal protein rpl10 using blastP | ||||||||
| Strain | WBStrain00047649 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00054607 | ||||||||
| 00054608 | |||||||||
| 00054609 | |||||||||
| 00054610 | |||||||||
| 00112824 | |||||||||
| 00112825 | |||||||||
| 00112826 | |||||||||
| Contained_in_operon | CEOP2340 | ||||||||
| Ortholog (43) | |||||||||
| Structured_description | Concise_description | rpl-10 encodes a large ribosomal subunit L10 protein required in mass RNAi assays for embryonic viability, fertility, normally rapid growth, and normal body coloration; the rpl-10 transcription unit has a nonsense transcript that is up-regulated in vivo by smg[-] mutations, indicating that rpl-10 is a natural substrate for SMG-mediated nonsense suppresssion; several other natural mRNA substrates of SMG suppression (e.g., rpl-3, rpl-7, rpl-12) have protein products that are involved in translation. | Paper_evidence | WBPaper00004313 | |||||
| WBPaper00004540 | |||||||||
| WBPaper00004651 | |||||||||
| WBPaper00005654 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Expressed in head; pharyngeal muscle cell; and tail. Human ortholog(s) of this gene implicated in autistic disorder; spermatogenic failure 63; and syndromic X-linked mental retardation 35. Is an ortholog of human RPL10 (ribosomal protein L10) and RPL10L (ribosomal protein L10 like). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0112356 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17976) | ||||
| DOID:12849 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10298) | ||||||
| DOID:0080241 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10298) | ||||||
| Molecular_info | Corresponding_CDS | F10B5.1 | |||||||
| Corresponding_transcript | F10B5.1.1 | ||||||||
| Other_sequence (421) | |||||||||
| Associated_feature | WBsf644443 | ||||||||
| WBsf654899 | |||||||||
| WBsf657205 | |||||||||
| WBsf657943 | |||||||||
| WBsf657944 | |||||||||
| WBsf221692 | |||||||||
| WBsf221693 | |||||||||
| Experimental_info | RNAi_result (19) | ||||||||
| Expr_pattern | Chronogram624 | ||||||||
| Expr98 | |||||||||
| Expr5711 | |||||||||
| Expr1019983 | |||||||||
| Expr1032225 | |||||||||
| Expr1148166 | |||||||||
| Expr2015437 | |||||||||
| Expr2033672 | |||||||||
| Drives_construct | WBCnstr00002441 | ||||||||
| WBCnstr00035500 | |||||||||
| Construct_product | WBCnstr00035500 | ||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (171) | |||||||||
| Interaction (260) | |||||||||
| Map_info | Map | II | Position | 0.711423 | Error | 0.00128 | |||
| Positive | Positive_clone | F10B5 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00004313 | ||||||||
| WBPaper00025088 | |||||||||
| WBPaper00030791 | |||||||||
| WBPaper00035149 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00060235 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
