rpy-1 is orthologous to the human gene 43KDA ACETYLCHOLINE RECEPTOR-ASSOCIATED PROTEIN (RAPSN; OMIM:601592), which when mutated leads to congenital myasthenic syndrome.
Predicted to enable acetylcholine receptor binding activity. Predicted to be involved in cholinergic synaptic transmission and positive regulation of neuromuscular synaptic transmission. Predicted to be located in neuromuscular junction and plasma membrane. Expressed in neurons. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 11 and fetal akinesia deformation sequence syndrome 2. Is an ortholog of human RAPSN (receptor associated protein of the synapse).
[Han M] ras-related protein. Very similar to mammalian rap1A (Krev).
This other_name rap-1 is not the same as the CGC main name rap-1 (C27B7.8)
CGC_data_submission
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.