WormBase Tree Display for Gene: WBGene00004778
expand all nodes | collapse all nodes | view schema
| WBGene00004778 | SMap | S_parent | Sequence | K02F2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | ser-3 | Person_evidence | WBPerson32 | |||||
| Sequence_name | K02F2.6 | ||||||||
| Molecular_name | K02F2.6 | ||||||||
| K02F2.6.1 | |||||||||
| CE17158 | |||||||||
| Other_name | K02F2.b | Curator_confirmed | WBPerson1983 | ||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| CELE_K02F2.6 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | ser-3 | ||||||||
| DB_info | Database | AceView | gene | 1H400 | |||||
| WormQTL | gene | WBGene00004778 | |||||||
| WormFlux | gene | WBGene00004778 | |||||||
| NDB | locus_tag | CELE_K02F2.6 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004778|UniProtKB=O44986 | |||||||
| family | PTHR24247 | ||||||||
| NCBI | gene | 259744 | |||||||
| RefSeq | protein | NM_059553.5 | |||||||
| TREEFAM | TREEFAM_ID | TF331895 | |||||||
| TrEMBL | UniProtAcc | O44986 | |||||||
| UniProt_GCRP | UniProtAcc | O44986 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ser | ||||||||
| Allele (33) | |||||||||
| Legacy_information | [Leon Avery] ad1774 deletes bp 433-1994 of K02F2.6. ad1774 mutants have no obvious phenotype. | ||||||||
| Strain | WBStrain00001799 | ||||||||
| WBStrain00032316 | |||||||||
| WBStrain00032325 | |||||||||
| WBStrain00005326 | |||||||||
| WBStrain00005587 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (22) | |||||||||
| Ortholog (27) | |||||||||
| Paralog (20) | |||||||||
| Structured_description | Concise_description | ser-3 encodes an octopamine receptor; ser-3 is required in the SIA neurons for response to the absence of food and to exogenous octopamine; SER-3 also mediates along with SER-4, the dietary restriction-based, lifespan-extending effects of mianserin, an antidepressant, on C. elegans; when expressed in HEK293 cells, SER-3 mediates a response to octopamine and to tyramine, but not serotonin; in addition, ser-3 is required for normal inhibition of movement by 5-HT, with ser-3 mutants being hyperactive and excessively curling their male tails (but this phenotype is reversed by exogenous 5-HT, with ser-3 mutants then becoming sluggish); ser-3 activity is also required for normally high brood sizes and for embryonic development, and weakly required for pharyngeal pumping; SER-3 is expressed in pharynx, head and tail neurons, nerve ring, and intestine. | Paper_evidence | WBPaper00004651 | |||||
| WBPaper00006180 | |||||||||
| WBPaper00006525 | |||||||||
| WBPaper00024527 | |||||||||
| WBPaper00028762 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 20 Dec 2006 00:00:00 | ||||||||
| Automated_description | Enables octopamine receptor activity. Involved in octopamine or tyramine signaling pathway. Predicted to be located in dendrite. Expressed in several structures, including ASH; SIA; head muscle; hermaphrodite gonad; and lumbar ganglion. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | K02F2.6 | |||||||
| Corresponding_transcript | K02F2.6.1 | ||||||||
| Other_sequence (22) | |||||||||
| Associated_feature | WBsf219646 | ||||||||
| WBsf219647 | |||||||||
| Experimental_info | RNAi_result (27) | ||||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00000006 | ||||||||
| WBCnstr00002600 | |||||||||
| WBCnstr00013231 | |||||||||
| WBCnstr00017413 | |||||||||
| WBCnstr00035393 | |||||||||
| Construct_product | WBCnstr00017413 | ||||||||
| WBCnstr00035393 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (124) | |||||||||
| Interaction | WBInteraction000275235 | ||||||||
| WBInteraction000348503 | |||||||||
| WBInteraction000348812 | |||||||||
| WBInteraction000349941 | |||||||||
| WBInteraction000394261 | |||||||||
| WBInteraction000409774 | |||||||||
| WBInteraction000425379 | |||||||||
| WBProcess | WBbiopr:00000001 | ||||||||
| Map_info | Map | I | Position | 1.33662 | Error | 0.005477 | |||
| Positive | Positive_clone | K02F2 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4655 | |||||||
| 4962 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (35) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
