WormBase Tree Display for Gene: WBGene00004896
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| WBGene00004896 | SMap | S_parent | Sequence | Y49F6B | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | smu-2 | Person_evidence | WBPerson252 | |||||
| Sequence_name | Y49F6B.4 | ||||||||
| Molecular_name | Y49F6B.4 | ||||||||
| Y49F6B.4.1 | |||||||||
| CE25338 | |||||||||
| Other_name | CELE_Y49F6B.4 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | smu-2 | ||||||||
| DB_info | Database | AceView | gene | 2D779 | |||||
| WormQTL | gene | WBGene00004896 | |||||||
| WormFlux | gene | WBGene00004896 | |||||||
| NDB | locus_tag | CELE_Y49F6B.4 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004896|UniProtKB=Q9N4U5 | |||||||
| family | PTHR12765 | ||||||||
| NCBI | gene | 173693 | |||||||
| RefSeq | protein | NM_062158.5 | |||||||
| SwissProt | UniProtAcc | Q9N4U5 | |||||||
| TREEFAM | TREEFAM_ID | TF321907 | |||||||
| UniProt_GCRP | UniProtAcc | Q9N4U5 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:36 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | smu | ||||||||
| Allele (258) | |||||||||
| Legacy_information | [Lundquist EA] smu for suppressor of mec-8 and unc-52. Suppresses Mec (touch insensitive) and Dyf (dye-filling defective) phenes of mec-8(u218ts), Mec phene of mec-8(mn472ts), Dyf phene of most mec-8 alleles, variable cold-sensitive arrest of mec-8(u74) and mec-8(mn463), Unc phene of unc-52(e669su250ts) and synthetic lethality of mec-8(u218ts) unc-52(e669su250ts). Essentially wild-type phenotype by itself. | ||||||||
| [C.elegansII] mn416 : suppresses Mec (touch insensitive) and Dyf (dye-filling defective) phenes of mec-8(u218ts), Mec phene of mec-8(mn472ts), Dyf phene of most mec-8 alleles, variable cold-sensitive arrest of mec-8(u74) and mec-8(mn463), Unc phene of unc-52(e669su250ts) and synthetic lethality of mec-8(u218ts); unc-52(e669su250ts). Essentially WT alone. [Lundquist and Herman 1994; SP] | |||||||||
| Complementation_data | [Lundquist EA] Complements mup-1(e2436) | ||||||||
| Strain | WBStrain00034411 | ||||||||
| WBStrain00034394 | |||||||||
| WBStrain00034413 | |||||||||
| WBStrain00034415 | |||||||||
| WBStrain00054680 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (36) | |||||||||
| Structured_description | Concise_description | smu-2 encodes a protein with homology to the mammalian nuclear protein RED that affects the accumulation of alternatively spliced unc-52 transcripts; SMU-2 activity is required, along with that of SMU-1, for regulation of splice site choice in the pre-mRNAs of unc-52 and other genes; SMU-2 physically interacts with SMU-1 both in vitro and in vivo, and stabilizes SMU-1; SMU-2 is ubiquitously expressed and localizes to both the nucleus and the nucleolus. | Paper_evidence | WBPaper00004764 | |||||
| WBPaper00024265 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 14 May 2014 00:00:00 | ||||||||
| Automated_description | Involved in several processes, including mechanosensory behavior; nematode larval development; and regulation of alternative mRNA splicing, via spliceosome. Located in nucleolus. Expressed widely. Is an ortholog of human IK (IK cytokine). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y49F6B.4 | |||||||
| Corresponding_transcript | Y49F6B.4.1 | ||||||||
| Other_sequence (40) | |||||||||
| Associated_feature | WBsf644067 | ||||||||
| WBsf657423 | |||||||||
| WBsf981179 | |||||||||
| WBsf221018 | |||||||||
| WBsf221019 | |||||||||
| Experimental_info | RNAi_result (13) | ||||||||
| Expr_pattern | Expr3427 | ||||||||
| Expr1025656 | |||||||||
| Expr1032435 | |||||||||
| Expr1160483 | |||||||||
| Expr2015930 | |||||||||
| Expr2034163 | |||||||||
| Drives_construct | WBCnstr00000998 | ||||||||
| WBCnstr00000999 | |||||||||
| WBCnstr00001003 | |||||||||
| WBCnstr00016044 | |||||||||
| WBCnstr00016046 | |||||||||
| WBCnstr00016050 | |||||||||
| Construct_product | WBCnstr00016045 | ||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (126) | |||||||||
| Interaction (41) | |||||||||
| Map_info | Map | II | Position | -6.254 | Error | 0.004598 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | Y49F6B | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | 2_point | 6213 | |||||||
| Multi_point | 2771 | ||||||||
| 2772 | |||||||||
| 2773 | |||||||||
| 2774 | |||||||||
| 5440 | |||||||||
| 5672 | |||||||||
| Reference (23) | |||||||||
| Method | Gene |
