WormBase Tree Display for Gene: WBGene00004986
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WBGene00004986 | SMap | S_parent | Sequence | T07C4 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | spp-1 | |||||||
Sequence_name | T07C4.4 | ||||||||
Molecular_name | T07C4.4 | ||||||||
T07C4.4.1 | |||||||||
CE35363 | |||||||||
Other_name | CELE_T07C4.4 | Accession_evidence | NDB | BX284603 | |||||
Public_name | spp-1 | ||||||||
DB_info | Database | AceView | gene | 3L444 | |||||
WormQTL | gene | WBGene00004986 | |||||||
WormFlux | gene | WBGene00004986 | |||||||
NDB | locus_tag | CELE_T07C4.4 | |||||||
NCBI | gene | 176452 | |||||||
RefSeq | protein | NM_066889.8 | |||||||
TREEFAM | TREEFAM_ID | TF322432 | |||||||
TrEMBL | UniProtAcc | Q22291 | |||||||
UniProt_GCRP | UniProtAcc | Q22291 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:37 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | spp | ||||||||
Allele | WBVar01500260 | ||||||||
WBVar01499545 | |||||||||
WBVar00407186 | |||||||||
WBVar01499774 | |||||||||
WBVar02019092 | |||||||||
WBVar00093807 | |||||||||
WBVar00252252 | |||||||||
WBVar00855993 | |||||||||
Strain | WBStrain00032729 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (14) | |||||||||
Contained_in_operon | CEOP3839 | ||||||||
Ortholog (22) | |||||||||
Paralog | WBGene00004997 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Inparanoid_8 | |||||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | spp-1 encodes a caenopore, a saposin (B) domain-containing protein that is a member of the saposin-like protein (SAPLIP) superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapore-like proteins; SPP-1 exhibits antibacterial activity in vitro and its expression in vivo is regulated by the DAF-2/insulin receptor signaling pathway and by the presence of bacterial pathogens such as Salmonella typhimurium and Pseudomonas aeruginosa; an spp-1::gfp reporter fusion is expressed in the intestine. | Paper_evidence | WBPaper00003435 | |||||
WBPaper00005976 | |||||||||
WBPaper00029438 | |||||||||
WBPaper00031463 | |||||||||
WBPaper00032276 | |||||||||
WBPaper00035289 | |||||||||
WBPaper00041035 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 05 Jul 2012 00:00:00 | ||||||||
Automated_description | Enables pore-forming activity. Involved in defense response to other organism and pore formation in membrane of another organism. Part of pore complex. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | T07C4.4 | |||||||
Corresponding_CDS_history | T07C4.4:wp108 | ||||||||
Corresponding_transcript | T07C4.4.1 | ||||||||
Other_sequence | CR10745 | ||||||||
CBC10698_1 | |||||||||
CRC07559_1 | |||||||||
Associated_feature | WBsf227443 | ||||||||
Experimental_info | RNAi_result (34) | ||||||||
Expr_pattern | Expr4718 | ||||||||
Expr8002 | |||||||||
Expr1020872 | |||||||||
Expr1032482 | |||||||||
Expr1156337 | |||||||||
Expr2016075 | |||||||||
Expr2034311 | |||||||||
Drives_construct (2) | |||||||||
Construct_product | WBCnstr00012195 | ||||||||
WBCnstr00035291 | |||||||||
Microarray_results (25) | |||||||||
Expression_cluster (247) | |||||||||
Interaction (20) | |||||||||
WBProcess | WBbiopr:00000008 | ||||||||
WBbiopr:00000039 | |||||||||
Map_info | Map | III | Position | 2.4671 | Error | 0.002388 | |||
Positive | Positive_clone | T07C4 | Inferred_automatically | From CDS info | |||||
From sequence, transcript, pseudogene data | |||||||||
Pseudo_map_position | |||||||||
Reference (34) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |