WormBase Tree Display for Gene: WBGene00006379
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| WBGene00006379 | SMap | S_parent | Sequence | T23D8 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | sys-1 | Person_evidence | WBPerson320 | |||||
| Sequence_name | T23D8.9 | ||||||||
| Molecular_name | T23D8.9a | ||||||||
| T23D8.9a.1 | |||||||||
| CE18959 | |||||||||
| T23D8.9b | |||||||||
| CE27209 | |||||||||
| T23D8.9c | |||||||||
| CE50477 | |||||||||
| T23D8.9b.1 | |||||||||
| T23D8.9c.1 | |||||||||
| Other_name | CELE_T23D8.9 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | sys-1 | ||||||||
| DB_info | Database | AceView | gene | 1K556 | |||||
| WormQTL | gene | WBGene00006379 | |||||||
| SignaLink | protein | WBGene00006379 | |||||||
| WormFlux | gene | WBGene00006379 | |||||||
| NDB | locus_tag | CELE_T23D8.9 | |||||||
| NCBI | gene | 172859 | |||||||
| RefSeq | protein | NM_060238.6 | |||||||
| NM_001392922.1 | |||||||||
| NM_001313509.3 | |||||||||
| TrEMBL | UniProtAcc | Q9XVI2 | |||||||
| A0A0K3ARA0 | |||||||||
| Q95ZN3 | |||||||||
| UniProt_GCRP | UniProtAcc | Q9XVI2 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 26 Jul 2005 13:20:15 | WBPerson2970 | Event | Acquires_merge | WBGene00011946 | ||||
| Acquires_merge | WBGene00011946 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sys | ||||||||
| Allele (61) | |||||||||
| Strain | WBStrain00022575 | ||||||||
| WBStrain00022587 | |||||||||
| WBStrain00022589 | |||||||||
| WBStrain00022617 | |||||||||
| WBStrain00022636 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (48) | |||||||||
| Ortholog (22) | |||||||||
| Structured_description | Concise_description | sys-1 encodes a novel protein that contains three divergent armadillo repeats; during gonadogenesis, SYS-1 functions in a Wnt/MAPK signaling pathway as a dosage-dependent beta-catenin-like transcriptional coactivator required for specification of distal cell fates; consistent with its role as a beta-catenin, SYS-1 interacts, in yeast two-hybrid and coimmunoprecipitation assays, with the POP-1/TCF transcription factor with which it can stimulate transcription via TCF binding sites; in two hybrid-assays, the POP-1/SYS-1 interaction requires the N-terminal beta-catenin binding domain of POP-1, and most of the SYS-1 protein; a VNS::SYS-1 reporter fusion protein is expressed in several tissues during embryonic and larval development and localizes to both the nucleus and cytoplasm as well as to what appears to be the centrosomes; in many tissues, SYS-1 is distributed asymmetrically, in a manner reciprocal to the asymmetric distribution of POP-1. | Paper_evidence | WBPaper00004521 | |||||
| WBPaper00006440 | |||||||||
| WBPaper00026603 | |||||||||
| WBPaper00029120 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 09 Oct 2007 00:00:00 | ||||||||
| Automated_description | Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; scaffold protein binding activity; and transcription coactivator activity. Involved in several processes, including cell fate commitment involved in formation of primary germ layer; gonad development; and regulation of gene expression. Located in several cellular components, including cell cortex; kinetochore; and pericentriolar material. Expressed in several structures, including ABplpapaap; ABprpapaap; Z1.aa; posterior distal tip cell; and tail hypodermis. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T23D8.9a | |||||||
| T23D8.9b | |||||||||
| T23D8.9c | |||||||||
| Corresponding_CDS_history | T23D8.9:wp47 | ||||||||
| Corresponding_transcript | T23D8.9a.1 | ||||||||
| T23D8.9b.1 | |||||||||
| T23D8.9c.1 | |||||||||
| Other_sequence | CJC02991_1 | ||||||||
| CRC06656_1 | |||||||||
| Associated_feature | WBsf649538 | ||||||||
| WBsf649539 | |||||||||
| WBsf663824 | |||||||||
| WBsf664813 | |||||||||
| WBsf664814 | |||||||||
| WBsf664815 | |||||||||
| WBsf984874 | |||||||||
| WBsf1010464 | |||||||||
| WBsf220181 | |||||||||
| WBsf220182 | |||||||||
| Experimental_info | RNAi_result (86) | ||||||||
| Expr_pattern (12) | |||||||||
| Drives_construct | WBCnstr00001897 | ||||||||
| WBCnstr00001902 | |||||||||
| WBCnstr00001903 | |||||||||
| WBCnstr00001904 | |||||||||
| WBCnstr00008170 | |||||||||
| WBCnstr00019269 | |||||||||
| WBCnstr00019839 | |||||||||
| WBCnstr00034381 | |||||||||
| Construct_product (11) | |||||||||
| Antibody | WBAntibody00000851 | ||||||||
| Microarray_results (36) | |||||||||
| Expression_cluster (166) | |||||||||
| Interaction (91) | |||||||||
| WBProcess | WBbiopr:00000073 | ||||||||
| WBbiopr:00000114 | |||||||||
| Map_info | Map | I | Position | 4.13437 | Error | 0.001519 | |||
| Positive | Positive_clone | T23D8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5650 | |||||||
| Pseudo_map_position | |||||||||
| Reference (95) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
