WormBase Tree Display for Gene: WBGene00006411
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| WBGene00006411 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F14D12 | ||||||
| Identity | Version | 2 | |||||||
| Name | CGC_name | octr-1 | Person_evidence | WBPerson3043 | |||||
| Sequence_name | F14D12.6 | ||||||||
| Molecular_name | F14D12.6a | ||||||||
| F14D12.6a.1 | |||||||||
| CE35478 | |||||||||
| F14D12.6b | |||||||||
| CE35479 | |||||||||
| F14D12.6b.1 | |||||||||
| Other_name | tag-24 | Person_evidence | WBPerson201 | ||||||
| CELE_F14D12.6 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | octr-1 | ||||||||
| DB_info | Database | AceView | gene | XG226 | |||||
| WormQTL | gene | WBGene00006411 | |||||||
| WormFlux | gene | WBGene00006411 | |||||||
| NDB | locus_tag | CELE_F14D12.6 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006411|UniProtKB=Q7JP61 | |||||||
| family | PTHR24247 | ||||||||
| NCBI | gene | 184469 | |||||||
| RefSeq | protein | NM_001029398.4 | |||||||
| NM_001029397.4 | |||||||||
| TrEMBL | UniProtAcc | Q7JP61 | |||||||
| Q7JP62 | |||||||||
| UniProt_GCRP | UniProtAcc | Q7JP61 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 11 Dec 2009 11:52:21 | WBPerson2970 | Name_change | CGC_name | octr-1 | ||||
| Other_name | tag-24 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | octr | ||||||||
| Allele (27) | |||||||||
| Strain | WBStrain00035596 | ||||||||
| WBStrain00005327 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (24) | |||||||||
| Ortholog (45) | |||||||||
| Paralog (14) | |||||||||
| Structured_description | Concise_description | octr-1 encodes a predicted G-protein-coupled seven-transmembrane domain biogenic amine receptor; OCTR-1, along with SER-3, plays a role in antagonistically modulating aversive behavior mediated by ASH neuronal signalling, with OCTR-1 signalling mediated by GOA-1 (G (o); OCTR-1 also plays a role in regulating the innate immune response and the unfolded protein response; an OCTR-1::GFP fusion protein is expressed in a very restricted pattern nearly exclusively in a subset of head and tail neurons. | Paper_evidence | WBPaper00006180 | |||||
| WBPaper00024527 | |||||||||
| WBPaper00043918 | |||||||||
| WBPaper00038304 | |||||||||
| WBPaper00040457 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 06 Mar 2014 00:00:00 | ||||||||
| Automated_description | Enables octopamine receptor activity. Involved in negative regulation of innate immune response; octopamine signaling pathway; and regulation of IRE1-mediated unfolded protein response. Predicted to be located in dendrite. Expressed in head neurons; sensory neurons; tail; uterine toroidal epithelial cell; and in male. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); attention deficit hyperactivity disorder; and type 2 diabetes mellitus. Is an ortholog of human ADRA2A (adrenoceptor alpha 2A). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:6000 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:283) | ||||
| DOID:1094 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:281) | ||||||
| DOID:9970 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:282) | ||||||
| DOID:9352 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:281,HGNC:282) | ||||||
| DOID:5844 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:282) | ||||||
| DOID:9743 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:282) | ||||||
| DOID:10763 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:281,HGNC:282) | ||||||
| Molecular_info | Corresponding_CDS | F14D12.6a | |||||||
| F14D12.6b | |||||||||
| Corresponding_CDS_history | F14D12.6:wp102 | ||||||||
| F14D12.6:wp108 | |||||||||
| Corresponding_transcript | F14D12.6a.1 | ||||||||
| F14D12.6b.1 | |||||||||
| Other_sequence (17) | |||||||||
| Associated_feature | WBsf1005321 | ||||||||
| WBsf1022980 | |||||||||
| WBsf237388 | |||||||||
| WBsf237389 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00072207 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00107776 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00044587 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030932 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00013265 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram292 | ||||||||
| Expr2714 | |||||||||
| Expr5757 | |||||||||
| Expr7846 | |||||||||
| Expr14337 | |||||||||
| Expr1010359 | |||||||||
| Expr1148544 | |||||||||
| Expr2014603 | |||||||||
| Expr2032836 | |||||||||
| Drives_construct | WBCnstr00000009 | ||||||||
| WBCnstr00002599 | |||||||||
| WBCnstr00008235 | |||||||||
| WBCnstr00012951 | |||||||||
| WBCnstr00037912 | |||||||||
| WBCnstr00040827 | |||||||||
| Construct_product | WBCnstr00008235 | ||||||||
| WBCnstr00008236 | |||||||||
| WBCnstr00012951 | |||||||||
| WBCnstr00037912 | |||||||||
| Regulate_expr_cluster | WBPaper00038304:octr-1_regulated | ||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (113) | |||||||||
| Interaction (37) | |||||||||
| WBProcess | WBbiopr:00000039 | ||||||||
| Map_info | Map | X | Position | -4.43509 | Error | 0.011598 | |||
| Positive | Positive_clone | F14D12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (41) | |||||||||
| Remark | Gene name created from parsing 'genotype' field from CGC strain information | CGC_data_submission | |||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
