WormBase Tree Display for Gene: WBGene00006435
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WBGene00006435 | Evidence | CGC_data_submission | |||||
---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | F25G6 | ||||
Identity | Version | 2 | |||||
Name | CGC_name | stdh-4 | |||||
Sequence_name | F25G6.5 | ||||||
Molecular_name | F25G6.5a | ||||||
F25G6.5a.1 | |||||||
CE47137 | |||||||
F25G6.5b | |||||||
CE52769 | |||||||
F25G6.5b.1 | |||||||
Other_name | tag-57 | Person_evidence | WBPerson201 | ||||
CELE_F25G6.5 | Accession_evidence | NDB | BX284605 | ||||
Public_name | stdh-4 | ||||||
DB_info | Database (13) | ||||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | stdh | ||||||
Allele (28) | |||||||
Strain | WBStrain00002288 | ||||||
WBStrain00035663 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00003241 | ||||||
00003242 | |||||||
00003243 | |||||||
00003244 | |||||||
00028932 | |||||||
00028933 | |||||||
Ortholog (67) | |||||||
Paralog (38) | |||||||
Structured_description | Concise_description | stdh-4 encodes a putative steroid dehydrogenase expressed in larval and adult pharynx; STDH-4 is orthologous to human HSD17B3 (OMIM:605573, mutated in pseudohermaphroditism), HSD17B12 (OMIM:609574), and HSDL1, and paralogous to LET-767 and STDH-1/-3; STDH-4 has no obvious function in mass RNAi assays. | Paper_evidence | WBPaper00006204 | |||
WBPaper00006525 | |||||||
WBPaper00031006 | |||||||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 26 Nov 2007 00:00:00 | ||||||
Automated_description | Predicted to enable oxidoreductase activity. Predicted to be involved in fatty acid elongation. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and Alzheimer's disease. Is an ortholog of human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5212) | ||
DOID:1923 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5212) | ||||
DOID:0112248 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:5212) | ||||
Molecular_info | Corresponding_CDS | F25G6.5a | |||||
F25G6.5b | |||||||
Corresponding_CDS_history | F25G6.5:wp230 | ||||||
Corresponding_transcript | F25G6.5a.1 | ||||||
F25G6.5b.1 | |||||||
Other_sequence (11) | |||||||
Associated_feature | WBsf718354 | ||||||
WBsf1000690 | |||||||
WBsf1000691 | |||||||
WBsf1000692 | |||||||
WBsf1020052 | |||||||
Experimental_info | RNAi_result | WBRNAi00045527 | Inferred_automatically | RNAi_primary | |||
WBRNAi00013885 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Chronogram1449 | ||||||
Chronogram1662 | |||||||
Expr5858 | |||||||
Expr1012380 | |||||||
Expr1149442 | |||||||
Expr2016959 | |||||||
Expr2035107 | |||||||
Drives_construct | WBCnstr00002988 | ||||||
WBCnstr00004487 | |||||||
WBCnstr00037909 | |||||||
Construct_product | WBCnstr00037909 | ||||||
Microarray_results (18) | |||||||
Expression_cluster (40) | |||||||
Interaction (90) | |||||||
Map_info | Map | V | Position | 1.4451 | Error | 0.002002 | |
Positive | Positive_clone | F25G6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 4869 | |||||
Pseudo_map_position | |||||||
Reference | WBPaper00018598 | ||||||
WBPaper00038491 | |||||||
WBPaper00042257 | |||||||
WBPaper00055090 | |||||||
Remark | Gene name created from parsing 'genotype' field from CGC strain information | CGC_data_submission | |||||
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||
Method | Gene |