WormBase Tree Display for Gene: WBGene00006443
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| WBGene00006443 | Evidence | CGC_data_submission | |||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | CHROMOSOME_V | ||||||
| Identity | Version | 3 | |||||||
| Name | CGC_name | pak-2 | Paper_evidence | WBPaper00028729 | |||||
| WBPaper00028826 | |||||||||
| Sequence_name | C45B11.1 | ||||||||
| Molecular_name | C45B11.1a | ||||||||
| C45B11.1a.1 | |||||||||
| CE40445 | |||||||||
| C45B11.1b | |||||||||
| CE40446 | |||||||||
| C45B11.1b.1 | |||||||||
| Other_name | tag-66 | Person_evidence | WBPerson201 | ||||||
| pak-4 | Person_evidence | WBPerson516 | |||||||
| CELE_C45B11.1 | Accession_evidence | NDB | BX284605 | ||||||
| Public_name | pak-2 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 08 Sep 2005 12:35:26 | WBPerson2970 | Name_change | CGC_name | pak-4 | ||||
| Other_name | tag-66 | ||||||||
| 3 | 04 Dec 2006 11:53:40 | WBPerson1847 | Name_change | CGC_name | pak-2 | ||||
| Other_name | pak-4 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | pak | ||||||||
| Allele (37) | |||||||||
| Strain | WBStrain00002747 | ||||||||
| WBStrain00003308 | |||||||||
| WBStrain00035624 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (46) | |||||||||
| Paralog (27) | |||||||||
| Structured_description | Concise_description | pak-2 encodes, by alternative splicing, at least two isoforms of aputative p21-activated kinase, orthologous to Drosophila melanogasterMUSHROOM BODIES TINY; pak-2 is expressed in pharynx, thepharyngeal-intestinal valve, vulva, and spermatheca; pak-2(ok332), aprobable null allele, has no obvious mutant phenotype in isolation andhas no effect on the axonal guidance phenotype of max-2(cy2), but showssome embryonic defects and L1 lethality as a double mutant with the nullpak-1(ok448). | Paper_evidence | WBPaper00006525 | |||||
| WBPaper00028729 | |||||||||
| WBPaper00028826 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 31 Jan 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable protein serine/threonine kinase activity. Involved in nematode larval development. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Is an ortholog of human PAK4 (p21 (RAC1) activated kinase 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:4467 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16059,HGNC:16061) | ||||
| Molecular_info | Corresponding_CDS | C45B11.1a | |||||||
| C45B11.1b | |||||||||
| Corresponding_CDS_history | C45B11.1a:wp165 | ||||||||
| C45B11.1b:wp165 | |||||||||
| Corresponding_transcript | C45B11.1a.1 | ||||||||
| C45B11.1b.1 | |||||||||
| Other_sequence (14) | |||||||||
| Associated_feature | WBsf653059 | ||||||||
| WBsf977276 | |||||||||
| WBsf977277 | |||||||||
| WBsf977278 | |||||||||
| WBsf1001253 | |||||||||
| WBsf1001254 | |||||||||
| WBsf1020391 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00115609 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00029823 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00061753 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00011968 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00115703 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00002111 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00115710 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00115608 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00042510 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram122 | ||||||||
| Chronogram1913 | |||||||||
| Expr5505 | |||||||||
| Expr5506 | |||||||||
| Expr1025477 | |||||||||
| Expr1032621 | |||||||||
| Expr1146495 | |||||||||
| Expr2014687 | |||||||||
| Expr2032920 | |||||||||
| Drives_construct | WBCnstr00003276 | ||||||||
| WBCnstr00003779 | |||||||||
| WBCnstr00034356 | |||||||||
| Construct_product | WBCnstr00034356 | ||||||||
| Microarray_results (28) | |||||||||
| Expression_cluster (142) | |||||||||
| Interaction (13) | |||||||||
| Map_info | Map | V | Position | 2.91077 | Error | 0.002732 | |||
| Positive | Positive_clone | C45B11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4141 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027258 | ||||||||
| WBPaper00028729 | |||||||||
| WBPaper00028826 | |||||||||
| WBPaper00035583 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059947 | |||||||||
| WBPaper00061476 | |||||||||
| Remark | Gene name created from parsing 'genotype' field from CGC strain information | CGC_data_submission | |||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
