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WormBase Tree Display for Gene: WBGene00006445

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Name Class

WBGene00006445SMapS_parentSequenceCHROMOSOME_I
IdentityVersion1
NameCGC_nametag-68Person_evidenceWBPerson201
Sequence_nameF37D6.6
Molecular_nameF37D6.6
F37D6.6.1
CE36156
Other_nameF37D6.aPaper_evidenceWBPaper00030983
CELE_F37D6.6Accession_evidenceNDBBX284601
Public_nametag-68
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:40WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classtag
Allele (56)
StrainWBStrain00035721
RNASeq_FPKM (74)
GO_annotation (16)
Ortholog (36)
ParalogWBGene00000904Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000910Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004856Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004857Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00004858Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00000899Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionAutomated_descriptionPredicted to enable I-SMAD binding activity and transcription regulator inhibitor activity. Predicted to be involved in several processes, including SMAD protein signal transduction; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Predicted to be part of heteromeric SMAD protein complex. Expressed in head neurons; intestine; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including aortic valve disease 2; idiopathic pulmonary fibrosis; and liver disease (multiple). Is an ortholog of human SMAD6 (SMAD family member 6) and SMAD7 (SMAD family member 7).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9256Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6773)
DOID:0080334Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6772)
DOID:0050156Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6772)
DOID:0060912Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6772)
DOID:1793Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6773)
DOID:5082Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6773)
DOID:9827Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6772)
DOID:684Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6773)
DOID:1380Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6773)
DOID:4074Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6773)
Molecular_infoCorresponding_CDSF37D6.6
Corresponding_CDS_historyF37D6.6:wp114
Corresponding_transcriptF37D6.6.1
Other_sequenceHG01978
Oden_isotig19148
JI172413.1
HGC02733_1
Associated_featureWBsf656866
WBsf716670
WBsf717566
WBsf717567
WBsf717568
WBsf985021
WBsf1010558
WBsf218433
WBsf218434
Transcription_factorWBTranscriptionFactor001003
Experimental_infoRNAi_resultWBRNAi00031923Inferred_automaticallyRNAi_primary
WBRNAi00003624Inferred_automaticallyRNAi_primary
WBRNAi00046643Inferred_automaticallyRNAi_primary
WBRNAi00016088Inferred_automaticallyRNAi_primary
WBRNAi00003625Inferred_automaticallyRNAi_primary
WBRNAi00107365Inferred_automaticallyRNAi_primary
Expr_patternExpr7544
Expr1022149
Expr1032623
Expr1150514
Expr2017289
Expr2035424
Drives_constructWBCnstr00012689
WBCnstr00034354
Construct_productWBCnstr00016828
WBCnstr00034354
Microarray_results (29)
Expression_cluster (122)
InteractionWBInteraction000527478
WBInteraction000528054
WBInteraction000535337
WBProcessWBbiopr:00000025
Map_infoMapIPosition5.05351Error0.00043
PositivePositive_cloneF37D6Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point4865
4833
Pseudo_map_position
ReferenceWBPaper00027307
WBPaper00030983
WBPaper00038487
WBPaper00048092
WBPaper00061709
WBPaper00061717
WBPaper00061738
RemarkGene name created from parsing 'genotype' field from CGC strain informationCGC_data_submission
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene