WormBase Tree Display for Gene: WBGene00006545
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| WBGene00006545 | SMap | S_parent | Sequence | T07C4 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | tbx-8 | |||||||
| Sequence_name | T07C4.2 | ||||||||
| Molecular_name | T07C4.2 | ||||||||
| T07C4.2.1 | |||||||||
| CE36891 | |||||||||
| T07C4.2.2 | |||||||||
| Other_name | CELE_T07C4.2 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | tbx-8 | ||||||||
| DB_info | Database | AceView | gene | 3L437 | |||||
| WormQTL | gene | WBGene00006545 | |||||||
| WormFlux | gene | WBGene00006545 | |||||||
| NDB | locus_tag | CELE_T07C4.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006545|UniProtKB=Q22292 | |||||||
| family | PTHR11267 | ||||||||
| NCBI | gene | 176450 | |||||||
| RefSeq | protein | NM_066886.6 | |||||||
| SwissProt | UniProtAcc | Q22292 | |||||||
| UniProt_GCRP | UniProtAcc | Q22292 | |||||||
| OMIM | gene | 601620 | |||||||
| 604616 | |||||||||
| 604895 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | tbx | ||||||||
| Allele (37) | |||||||||
| Legacy_information | [C.elegansII] NMK. Similarity to mouse Tbx genes; T07C4.2; related to tbx-9, divergent transcripts. [Agulnik et al. 1995] | ||||||||
| Strain | WBStrain00000302 | ||||||||
| WBStrain00031544 | |||||||||
| WBStrain00029978 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Ortholog (64) | |||||||||
| Paralog (21) | |||||||||
| Structured_description | Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic body morphogenesis. Located in nucleus. Expressed in several structures, including Eal; Ear; Epl; Epr; and intestine. Human ortholog(s) of this gene implicated in several diseases, including Holt-Oram syndrome; asthma, nasal polyps, and aspirin intolerance; and malaria. Is an ortholog of several human genes including EOMES (eomesodermin); TBR1 (T-box brain transcription factor 1); and TBX5 (T-box transcription factor 5). | Paper_evidence | WBPaper00065943 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11599) | ||||
| EFO:0003756 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11590) | ||||||
| DOID:12365 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11599) | ||||||
| DOID:0111579 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11599) | ||||||
| DOID:0060468 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11604) | ||||||
| Molecular_info | Corresponding_CDS | T07C4.2 | |||||||
| Corresponding_CDS_history | T07C4.2:wp126 | ||||||||
| Corresponding_transcript | T07C4.2.1 | ||||||||
| T07C4.2.2 | |||||||||
| Other_sequence | Dviv_isotig20305 | ||||||||
| ASC36756_1 | |||||||||
| JI177045.1 | |||||||||
| CBC07939_1 | |||||||||
| Oden_isotig25474 | |||||||||
| JI214463.1 | |||||||||
| FE917418.1 | |||||||||
| Associated_feature (11) | |||||||||
| Transcription_factor | WBTranscriptionFactor000321 | ||||||||
| Experimental_info | RNAi_result (40) | ||||||||
| Expr_pattern (15) | |||||||||
| Drives_construct | WBCnstr00001006 | ||||||||
| WBCnstr00001614 | |||||||||
| WBCnstr00009662 | |||||||||
| WBCnstr00009663 | |||||||||
| WBCnstr00012537 | |||||||||
| WBCnstr00012800 | |||||||||
| WBCnstr00012980 | |||||||||
| WBCnstr00015341 | |||||||||
| WBCnstr00015342 | |||||||||
| WBCnstr00034308 | |||||||||
| Construct_product | WBCnstr00001006 | ||||||||
| WBCnstr00005021 | |||||||||
| WBCnstr00015398 | |||||||||
| WBCnstr00034308 | |||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (99) | |||||||||
| Interaction (497) | |||||||||
| Map_info | Map | III | Position | 2.46132 | Error | 0.011618 | |||
| Positive | Positive_clone | T07C4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4790 | |||||||
| 4968 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (24) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
