WormBase Tree Display for Gene: WBGene00006614
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| WBGene00006614 | Evidence | Paper_evidence | WBPaper00006041 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| CGC_data_submission | |||||||||
| SMap | S_parent | Sequence | ZC21 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | trp-1 | Person_evidence | WBPerson625 | |||||
| Sequence_name | ZC21.2 | ||||||||
| Molecular_name | ZC21.2a | ||||||||
| ZC21.2a.1 | |||||||||
| CE33009 | |||||||||
| ZC21.2b | |||||||||
| CE54118 | |||||||||
| ZC21.2b.1 | |||||||||
| Other_name | strpc1 | Accession_evidence | EMBL | AJ276027 | |||||
| CELE_ZC21.2 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | trp-1 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00006614 | |||||
| WormFlux | gene | WBGene00006614 | |||||||
| NDB | locus_tag | CELE_ZC21.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006614|UniProtKB=P34586 | |||||||
| family | PTHR10117 | ||||||||
| NCBI | gene | 176202 | |||||||
| RefSeq | protein | NM_001379835.1 | |||||||
| NM_001047424.3 | |||||||||
| SwissProt | UniProtAcc | P34586 | |||||||
| TrEMBL | UniProtAcc | Q27GV1 | |||||||
| UniProt_GCRP | UniProtAcc | P34586 | |||||||
| OMIM | gene | 602345 | |||||||
| 603652 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:41 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | trp | ||||||||
| Allele (112) | |||||||||
| Strain | WBStrain00034932 | ||||||||
| WBStrain00035547 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (39) | |||||||||
| Paralog | WBGene00004976 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00006615 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | trp-1 encodes a transient receptor potential (TRP) channel that, along with TRP-2 and SPE-41, constitutes the three C. elegans members of the TRPC subfamily; trp-1, along with trp-2, control nicotine-dependent behavior; a TRP-1::GFP reporter fusion is expressed in motor neurons, interneurons, vulval and intestinal muscles, and the BAG sensory neuron. | Paper_evidence | WBPaper00002930 | |||||
| WBPaper00028761 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 18 May 2012 00:00:00 | ||||||||
| Automated_description | Predicted to enable inositol 1,4,5 trisphosphate binding activity and store-operated calcium channel activity. Predicted to be involved in calcium ion transmembrane transport; regulation of cytosolic calcium ion concentration; and single fertilization. Predicted to be located in plasma membrane. Predicted to be part of cation channel complex. Expressed in neurons and non-striated muscle. Used to study nicotine dependence. Human ortholog(s) of this gene implicated in several diseases, including cerebellar ataxia type 41; chronic fatigue syndrome; and focal segmental glomerulosclerosis 2. Is an ortholog of human TRPC3 (transient receptor potential cation channel subfamily C member 3); TRPC6 (transient receptor potential cation channel subfamily C member 6); and TRPC7 (transient receptor potential cation channel subfamily C member 7). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:0050742 | Homo sapiens | Paper_evidence | WBPaper00028761 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 31 May 2019 00:00:00 | ||||||||
| Potential_model | DOID:1324 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:20754) | |||||
| DOID:0080379 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12338) | ||||||
| DOID:1312 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12338) | ||||||
| DOID:6432 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12335,HGNC:12338) | ||||||
| DOID:0111129 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12338) | ||||||
| DOID:8544 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12338) | ||||||
| DOID:0111744 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12335) | ||||||
| Models_disease_asserted | WBDOannot00000685 | ||||||||
| Molecular_info | Corresponding_CDS | ZC21.2a | |||||||
| ZC21.2b | |||||||||
| Corresponding_CDS_history | ZC21.2:wp91 | ||||||||
| ZC21.2:wp155 | |||||||||
| ZC21.2b:wp275 | |||||||||
| Corresponding_transcript | ZC21.2a.1 | ||||||||
| ZC21.2b.1 | |||||||||
| Other_sequence | TSC09828_1 | ||||||||
| ES569920.1 | |||||||||
| Oden_isotig24964 | |||||||||
| GRC01451_1 | |||||||||
| GR12517 | |||||||||
| Oden_isotig24247 | |||||||||
| Associated_feature | WBsf645423 | ||||||||
| WBsf659317 | |||||||||
| WBsf659318 | |||||||||
| WBsf1015451 | |||||||||
| WBsf1015452 | |||||||||
| WBsf225437 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00021618 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00005236 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00005537 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00021617 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00058794 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00058793 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr66 | ||||||||
| Expr2586 | |||||||||
| Expr4866 | |||||||||
| Expr8201 | |||||||||
| Expr13782 | |||||||||
| Expr1021993 | |||||||||
| Expr1162217 | |||||||||
| Expr2017499 | |||||||||
| Expr2035638 | |||||||||
| Marker55 | |||||||||
| Drives_construct | WBCnstr00000829 | ||||||||
| WBCnstr00009925 | |||||||||
| WBCnstr00009926 | |||||||||
| WBCnstr00009927 | |||||||||
| WBCnstr00010863 | |||||||||
| WBCnstr00012294 | |||||||||
| WBCnstr00013177 | |||||||||
| WBCnstr00034266 | |||||||||
| WBCnstr00039994 | |||||||||
| Construct_product | WBCnstr00034266 | ||||||||
| Microarray_results (25) | |||||||||
| Expression_cluster (157) | |||||||||
| Interaction | WBInteraction000306937 | ||||||||
| WBInteraction000428985 | |||||||||
| Map_info | Map | III | Position | -0.253651 | Error | 0.00084 | |||
| Positive | Positive_clone | ZC21 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4740 | |||||||
| 4969 | |||||||||
| 5521 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (21) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
