WormBase Tree Display for Gene: WBGene00006762
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WBGene00006762 | SMap | S_parent | Sequence | Y37D8A | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 1 | |||||||
Name | CGC_name | unc-25 | Person_evidence | WBPerson261 | |||||
Sequence_name | Y37D8A.23 | ||||||||
Molecular_name | Y37D8A.23a | ||||||||
Y37D8A.23a.1 | |||||||||
CE20226 | |||||||||
Y37D8A.23b | |||||||||
CE31832 | |||||||||
Y37D8A.23c | |||||||||
CE32012 | |||||||||
Y37D8A.23b.1 | |||||||||
Y37D8A.23c.1 | |||||||||
Other_name | CELE_Y37D8A.23 | Accession_evidence | NDB | BX284603 | |||||
Public_name | unc-25 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 07 Apr 2004 11:29:42 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
Status | Live | ||||||||
Gene_info (12) | |||||||||
Disease_info | Experimental_model (3) | ||||||||
Potential_model (12) | |||||||||
Disease_relevance | Mutations in Glutamic acid decarboxylase (GAD1), the human ortholog of elegans unc-25, are associated with autosomal recessive spastic cerebral palsy, a movement disorder caused by abnormalities in the brain; studies in elegans show that unc-25 is required for gamma-amino-butyric acid (GABA) synthesis and GABA-mediated behavioral functions; various GABA mutants in elegans, like unc-25, the GABA vesicular transporters (unc-46 and unc-47), and the GABA-A receptor, unc-49, all present head-bobbing convulsions. | Homo sapiens | Paper_evidence | WBPaper00024523 | |||||
WBPaper00042136 | |||||||||
Accession_evidence | OMIM | 603513 | |||||||
605363 | |||||||||
Curator_confirmed | WBPerson324 | ||||||||
Date_last_updated | 22 Apr 2013 00:00:00 | ||||||||
Models_disease_in_annotation | WBDOannot00000163 | ||||||||
Models_disease_asserted | WBDOannot00000549 | ||||||||
WBDOannot00000702 | |||||||||
WBDOannot00000703 | |||||||||
Molecular_info | Corresponding_CDS | Y37D8A.23a | |||||||
Y37D8A.23b | |||||||||
Y37D8A.23c | |||||||||
Corresponding_transcript | Y37D8A.23a.1 | ||||||||
Y37D8A.23b.1 | |||||||||
Y37D8A.23c.1 | |||||||||
Other_sequence (65) | |||||||||
Associated_feature | WBsf645681 | ||||||||
WBsf994764 | |||||||||
WBsf994765 | |||||||||
WBsf1016280 | |||||||||
WBsf1016281 | |||||||||
WBsf1016282 | |||||||||
WBsf225951 | |||||||||
WBsf225952 | |||||||||
Experimental_info (9) | |||||||||
Map_info | Map | III | Position | 20.6616 | Error | 0.04207 | |||
Well_ordered | |||||||||
Positive | Positive_clone | Y37D8A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | 2_point (7) | ||||||||
Multi_point (42) | |||||||||
Pos_neg_data | 354 | ||||||||
8378 | |||||||||
8386 | |||||||||
8389 | |||||||||
8550 | |||||||||
Reference (216) | |||||||||
Method | Gene |