WormBase Tree Display for Gene: WBGene00006951
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| WBGene00006951 | SMap | S_parent | Sequence | W03D2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | wrt-5 | Person_evidence | WBPerson83 | |||||
| Sequence_name | W03D2.5 | ||||||||
| Molecular_name | W03D2.5a | ||||||||
| W03D2.5a.1 | |||||||||
| CE14514 | |||||||||
| W03D2.5b | |||||||||
| CE33717 | |||||||||
| W03D2.5c | |||||||||
| CE49119 | |||||||||
| W03D2.5b.1 | |||||||||
| W03D2.5c.1 | |||||||||
| Other_name | F35F11 | Paper_evidence | WBPaper00002823 | ||||||
| W03D2 | Paper_evidence | WBPaper00002823 | |||||||
| CELE_W03D2.5 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | wrt-5 | ||||||||
| DB_info | Database | WormQTL | gene | WBGene00006951 | |||||
| WormFlux | gene | WBGene00006951 | |||||||
| NDB | locus_tag | CELE_W03D2.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006951|UniProtKB=Q9U7D3 | |||||||
| family | PTHR46706 | ||||||||
| NCBI | gene | 177162 | |||||||
| RefSeq | protein | NM_001047530.4 | |||||||
| NM_001307477.3 | |||||||||
| NM_001047529.4 | |||||||||
| SwissProt | UniProtAcc | Q9U7D3 | |||||||
| TrEMBL | UniProtAcc | U4PM52 | |||||||
| UniProt_GCRP | UniProtAcc | Q9U7D3 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | wrt | ||||||||
| Allele (30) | |||||||||
| Strain | WBStrain00031556 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00100492 | ||||||||
| 00100493 | |||||||||
| 00100494 | |||||||||
| 00100495 | |||||||||
| 00100496 | |||||||||
| Ortholog (27) | |||||||||
| Paralog (24) | |||||||||
| Structured_description | Concise_description | wrt-5 encodes a secreted protein with an N-terminal signal sequence anda C-terminal Wart domain; WRT-5 is required for hypodermal integrity;wrt-5 mutants have cold-sensitive lethality with abnormally locatedadherens junctions, and with defective cuticle structure, adhesion, andmolting; by alternative splicing, wrt-5 also encodes a shorter protein;WRT-5 is expressed in seam cells and the excretory cell from thebeginning of embryonic morphogenesis to the adult stage, in the sixcells of the pharyngeal-intestinal valve and rectal valve in larvae andadults, in the gonadal sheath cells, spermathecal sheath cells, anduterus in adults, and in amphid and phasmid sheath, and interneuronsPVT, PVQL, and PVQR; pharyngeal WRT-5 expression cycles in parallel withmolting; the Wart domain is predicted to form a cysteine-crosslinkedprotein involved in intercellular signalling, and it has subtlesimilarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-5 isa paralog of WRT-3, which may enable the conditional viability of wrt-5mutants; all of WRT-5's functions in vivo may reflect common defects incholesterol-dependent hedgehog-like signalling or in vesicletrafficking. | Paper_evidence | WBPaper00002823 | |||||
| WBPaper00003717 | |||||||||
| WBPaper00005654 | |||||||||
| WBPaper00026841 | |||||||||
| WBPaper00027037 | |||||||||
| WBPaper00027263 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 07 Nov 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable signaling receptor binding activity. Predicted to be involved in cell communication. Predicted to be located in extracellular region. Expressed in several structures, including excretory system; hermaphrodite gonad; pharyngeal-intestinal valve; phasmid socket cell; and rectal valve cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | W03D2.5a | |||||||
| W03D2.5b | |||||||||
| W03D2.5c | |||||||||
| Corresponding_CDS_history | W03D2.5:wp154 | ||||||||
| W03D2.5b:wp102 | |||||||||
| Corresponding_transcript | W03D2.5a.1 | ||||||||
| W03D2.5b.1 | |||||||||
| W03D2.5c.1 | |||||||||
| Other_sequence | HCC01144_1 | ||||||||
| JI169705.1 | |||||||||
| HC03055 | |||||||||
| Oden_isotig20840 | |||||||||
| ACC00509_1 | |||||||||
| CBC09842_1 | |||||||||
| Acan_isotig11399 | |||||||||
| HBC07543_1 | |||||||||
| EX914041.1 | |||||||||
| Associated_feature | WBsf655505 | ||||||||
| WBsf718069 | |||||||||
| WBsf996167 | |||||||||
| WBsf996168 | |||||||||
| WBsf996169 | |||||||||
| WBsf1017183 | |||||||||
| WBsf1017184 | |||||||||
| WBsf229943 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00077011 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00027883 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00054675 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00076984 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00019552 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr645 | ||||||||
| Expr1025322 | |||||||||
| Expr1158215 | |||||||||
| Expr2018080 | |||||||||
| Expr2036218 | |||||||||
| Drives_construct | WBCnstr00000343 | ||||||||
| WBCnstr00012470 | |||||||||
| WBCnstr00034077 | |||||||||
| Construct_product | WBCnstr00034077 | ||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (76) | |||||||||
| Interaction | WBInteraction000005514 | ||||||||
| WBInteraction000502312 | |||||||||
| WBInteraction000509256 | |||||||||
| WBProcess | WBbiopr:00000123 | ||||||||
| Map_info | Map | IV | Position | -0.918194 | Error | 0.024505 | |||
| Positive | Positive_clone | W03D2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4746 | |||||||
| Pseudo_map_position | |||||||||
| Reference (13) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
