WormBase Tree Display for Gene: WBGene00006975
expand all nodes | collapse all nodes | view schema
| WBGene00006975 | SMap | S_parent | Sequence | F54F2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | zfp-1 | |||||||
| Sequence_name | F54F2.2 | ||||||||
| Molecular_name (17) | |||||||||
| Other_name | zpf-1 | ||||||||
| CELE_F54F2.2 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | zfp-1 | ||||||||
| DB_info | Database | AceView | gene | 3J897 | |||||
| WormQTL | gene | WBGene00006975 | |||||||
| WormFlux | gene | WBGene00006975 | |||||||
| NDB | locus_tag | CELE_F54F2.2 | |||||||
| NCBI | gene | 176237 | |||||||
| RefSeq | protein | NM_001382948.2 | |||||||
| NM_001027439.2 | |||||||||
| NM_001392166.1 | |||||||||
| NR_136383.1 | |||||||||
| SwissProt | UniProtAcc | P34447 | |||||||
| UniProt_GCRP | UniProtAcc | P34447 | |||||||
| OMIM | gene | 602409 | |||||||
| RNAcentral | URSid | URS0000A0504F | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:44 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | zfp | ||||||||
| Allele (222) | |||||||||
| Strain | WBStrain00031487 | ||||||||
| WBStrain00000129 | |||||||||
| WBStrain00000130 | |||||||||
| WBStrain00000131 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (19) | |||||||||
| Ortholog (38) | |||||||||
| Paralog | WBGene00006975 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | |||||
| WBGene00003034 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00013339 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00021810 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | zfp-1 encodes a leucine zipper, zinc finger, and PHD/LAP domain (plant homeodomain/leukemia-associated protein)-containing protein homologous to human AF10 (OMIM:602409, which is involved in chromosomal translocations associated with acute leukemia); loss of zfp-1 activity via RNA-mediated interference (RNAi) results in suppression of RNAi, suggesting that ZFP-1 plays a role in gene silencing; based on sequence similarity, ZFP-1 is predicted to associate with chromatin. | Paper_evidence | WBPaper00005193 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Enables chromatin binding activity and methylated histone binding activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Located in condensed chromosome and nucleus. Expressed in several structures, including germ line; intestine; oocyte; pharynx; and seam cell. Human ortholog(s) of this gene implicated in acute monocytic leukemia and acute myeloid leukemia. Is an ortholog of human MLLT10 (MLLT10 histone lysine methyltransferase DOT1L cofactor) and MLLT6 (MLLT6, PHD finger containing). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:8864 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16063) | ||||
| DOID:9119 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16063) | ||||||
| Molecular_info | Corresponding_CDS | F54F2.2a | |||||||
| F54F2.2b | |||||||||
| F54F2.2c | |||||||||
| Corresponding_transcript (11) | |||||||||
| Other_sequence (17) | |||||||||
| Associated_feature (48) | |||||||||
| Experimental_info | RNAi_result (49) | ||||||||
| Expr_pattern | Expr107 | ||||||||
| Expr10609 | |||||||||
| Expr13643 | |||||||||
| Expr13644 | |||||||||
| Expr1012254 | |||||||||
| Expr1032980 | |||||||||
| Expr1152158 | |||||||||
| Expr2018128 | |||||||||
| Expr2036265 | |||||||||
| Drives_construct | WBCnstr00017394 | ||||||||
| WBCnstr00034060 | |||||||||
| WBCnstr00039923 | |||||||||
| WBCnstr00039924 | |||||||||
| Construct_product | WBCnstr00015783 | ||||||||
| WBCnstr00015784 | |||||||||
| WBCnstr00015785 | |||||||||
| WBCnstr00018587 | |||||||||
| WBCnstr00018588 | |||||||||
| WBCnstr00019015 | |||||||||
| WBCnstr00019016 | |||||||||
| WBCnstr00019017 | |||||||||
| WBCnstr00019018 | |||||||||
| WBCnstr00034060 | |||||||||
| Regulate_expr_cluster | WBPaper00032425:down_in_zfp-1 | ||||||||
| WBPaper00032425:up_in_zfp-1 | |||||||||
| Antibody | WBAntibody00002277 | ||||||||
| WBAntibody00002470 | |||||||||
| WBAntibody00002471 | |||||||||
| Microarray_results (44) | |||||||||
| Expression_cluster (135) | |||||||||
| Interaction (66) | |||||||||
| Map_info | Map | III | Position | -0.050086 | Error | 0.000742 | |||
| Positive | Positive_clone | F54F2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4763 | |||||||
| 5287 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (48) | |||||||||
| Remark | Other name 'zpf-1' was possibly just a typo for zfp-1 (in the relevant paper). The object corresponding to zpf-1 has been removed [krb 030807] | Paper_evidence | WBPaper00005194 | ||||||
| Person_evidence | WBPerson567 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
