WormBase Tree Display for Gene: WBGene00007024
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WBGene00007024 | Evidence | Author_evidence | Bourbon H-M | ||||||
---|---|---|---|---|---|---|---|---|---|
SMap | S_parent | Sequence | W01A8 | ||||||
Identity | Version | 2 | |||||||
Name | CGC_name | plin-1 | Paper_evidence | WBPaper00046584 | |||||
Person_evidence | WBPerson344 | ||||||||
Sequence_name | W01A8.1 | ||||||||
Molecular_name | W01A8.1a | ||||||||
W01A8.1a.1 | |||||||||
CE18303 | |||||||||
W01A8.1b | |||||||||
CE06531 | |||||||||
W01A8.1c | |||||||||
CE41705 | |||||||||
W01A8.1b.1 | |||||||||
W01A8.1b.2 | |||||||||
W01A8.1c.1 | |||||||||
Other_name | mdt-28 | ||||||||
CELE_W01A8.1 | Accession_evidence | NDB | BX284601 | ||||||
Public_name | plin-1 | ||||||||
DB_info | Database | AceView | gene | 1H635 | |||||
WormQTL | gene | WBGene00007024 | |||||||
WormFlux | gene | WBGene00007024 | |||||||
NDB | locus_tag | CELE_W01A8.1 | |||||||
NCBI | gene | 172437 | |||||||
RefSeq | protein | NM_001026475.4 | |||||||
NM_001026476.5 | |||||||||
NM_001129054.5 | |||||||||
SwissProt | UniProtAcc | A8WHP8 | |||||||
TREEFAM | TREEFAM_ID | TF343355 | |||||||
UniProt_GCRP | UniProtAcc | A8WHP8 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 14 May 2004 11:48:16 | WBPerson1845 | Event | Created | |||
2 | 25 Mar 2015 16:36:59 | WBPerson2970 | Name_change | CGC_name | plin-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | plin | ||||||||
Allele (40) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00005336 | ||||||||
00005337 | |||||||||
00005338 | |||||||||
Ortholog (29) | |||||||||
Structured_description | Concise_description | plin-1 encodes a mammalian perilipin homolog, the similarity appears clearly in profile-to-sequence (PSI-BLAST) and profile-to-profile (HHpred) searches; mammalian perilipin family proteins coat lipid droplets (LDs) sub-cellularly and are known to regulate the size and formation of LDs; perilipins are also known to interact with adipose triglyceride lipases (ATGL) and hormone sensitive lipases (HSL) and thus regulate lipolysis; PLIN-1 in C. elegans is expressed primarily in embryos, intestinal cells, epidermal cells, muscle cells and the pharynx; PLIN-1 null mutants are viable under laboratory conditions but show defects in lipid droplet size and number, with contrasting phenotype in the somatic and embryonic tissue. | Paper_evidence | WBPaper00006530 | |||||
WBPaper00027365 | |||||||||
WBPaper00027758 | |||||||||
WBPaper00048536 | |||||||||
WBPaper00046861 | |||||||||
WBPaper00046981 | |||||||||
Person_evidence | WBPerson13449 | ||||||||
Curator_confirmed | WBPerson1843 | ||||||||
WBPerson324 | |||||||||
Date_last_updated | 28 Oct 2015 00:00:00 | ||||||||
Automated_description | Involved in embryo development. Predicted to be located in lipid droplet. Expressed in germ line; hypodermal cell; and intestinal cell. | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | W01A8.1a | |||||||
W01A8.1b | |||||||||
W01A8.1c | |||||||||
Corresponding_transcript | W01A8.1a.1 | ||||||||
W01A8.1b.1 | |||||||||
W01A8.1b.2 | |||||||||
W01A8.1c.1 | |||||||||
Other_sequence (12) | |||||||||
Associated_feature | WBsf643420 | ||||||||
WBsf654800 | |||||||||
WBsf656485 | |||||||||
WBsf984072 | |||||||||
WBsf1010024 | |||||||||
WBsf217936 | |||||||||
WBsf217937 | |||||||||
WBsf217938 | |||||||||
WBsf217939 | |||||||||
Experimental_info | RNAi_result | WBRNAi00054489 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00004352 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00117402 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00117401 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00117403 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00036131 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00087244 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00114339 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00085250 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00117400 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr4157 | ||||||||
Expr13641 | |||||||||
Expr1016392 | |||||||||
Expr1033013 | |||||||||
Expr1158037 | |||||||||
Expr2014957 | |||||||||
Expr2033192 | |||||||||
Drives_construct | WBCnstr00021709 | ||||||||
WBCnstr00037878 | |||||||||
WBCnstr00039921 | |||||||||
WBCnstr00039922 | |||||||||
Construct_product | WBCnstr00021709 | ||||||||
WBCnstr00037878 | |||||||||
WBCnstr00039921 | |||||||||
WBCnstr00039922 | |||||||||
Antibody | WBAntibody00002636 | ||||||||
Microarray_results (34) | |||||||||
Expression_cluster (187) | |||||||||
Interaction (33) | |||||||||
Map_info | Map | I | Position | 1.68481 | Error | 0.004339 | |||
Positive | Positive_clone | W01A8 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Mapping_data | Multi_point | 4547 | |||||||
5026 | |||||||||
Pseudo_map_position | |||||||||
Reference (12) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
plin-1 was previously named incorrectly as mdt-28 | Paper_evidence | WBPaper00046584 | |||||||
Method | Gene |