WormBase Tree Display for Gene: WBGene00007126
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| WBGene00007126 | SMap | S_parent | Sequence | B0250 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | dhcr-7 | Person_evidence | WBPerson1847 | |||||
| Sequence_name | B0250.9 | ||||||||
| Molecular_name | B0250.9 | ||||||||
| B0250.9.1 | |||||||||
| CE36579 | |||||||||
| Other_name | CELE_B0250.9 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | dhcr-7 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:47 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 08 Jan 2009 14:53:29 | WBPerson2970 | Name_change | CGC_name | dhcr-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dhcr | ||||||||
| Allele (188) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00013525 | ||||||||
| 00013526 | |||||||||
| 00013527 | |||||||||
| 00013528 | |||||||||
| 00013529 | |||||||||
| 00115339 | |||||||||
| 00115340 | |||||||||
| 00115341 | |||||||||
| Ortholog (56) | |||||||||
| Paralog | WBGene00050927 | Caenorhabditis elegans | From_analysis | modENCODE_Pseudogenes | |||||
| Structured_description | Concise_description | dhcr-7 encodes a protein orthologous to the human 7-DEHYDROCHOLESTEROL REDUCTASE (DHCR7; OMIM:602858), which when mutated leads to disease. | Curator_confirmed | WBPerson1843 | |||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 14 Dec 2009 00:00:00 | ||||||||
| Automated_description | Predicted to enable 7-dehydrocholesterol reductase activity and sterol delta7 reductase activity. Predicted to be involved in brassinosteroid biosynthetic process and cholesterol biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in several diseases, including Greenberg dysplasia; Pelger-Huet anomaly; and Smith-Lemli-Opitz syndrome. Is an ortholog of human DHCR7 (7-dehydrocholesterol reductase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111588 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6518) | ||||
| DOID:12236 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6518) | ||||||
| DOID:9631 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6518) | ||||||
| DOID:14692 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2860) | ||||||
| DOID:13241 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2860) | ||||||
| Molecular_info | Corresponding_CDS | B0250.9 | |||||||
| Corresponding_CDS_history | B0250.9:wp123 | ||||||||
| Corresponding_transcript | B0250.9.1 | ||||||||
| Other_sequence (28) | |||||||||
| Associated_feature | WBsf717296 | ||||||||
| WBsf1003571 | |||||||||
| WBsf1003572 | |||||||||
| WBsf1021969 | |||||||||
| Experimental_info | RNAi_result (15) | ||||||||
| Expr_pattern | Expr1023603 | ||||||||
| Expr1033064 | |||||||||
| Expr1143012 | |||||||||
| Expr2010874 | |||||||||
| Expr2029113 | |||||||||
| Microarray_results (23) | |||||||||
| Expression_cluster (107) | |||||||||
| Interaction (45) | |||||||||
| Map_info | Map | V | Position | 25.0002 | Error | 0.000634 | |||
| Positive | Positive_clone | B0250 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
