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WormBase Tree Display for Gene: WBGene00007194

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Name Class

WBGene00007194SMapS_parentSequenceB0491
IdentityVersion2
NameCGC_namedph-5Person_evidenceWBPerson3778
Sequence_nameB0491.7
Molecular_nameB0491.7
B0491.7.1
CE02109
Other_nameCELE_B0491.7Accession_evidenceNDBBX284602
Public_namedph-5
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:47WBPerson1971EventImportedInitial conversion from CDS class of WS125
211 Jun 2021 18:11:09WBPerson1983Name_changeCGC_namedph-5
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classdph
Allele (22)
RNASeq_FPKM (74)
GO_annotation00058310
00058311
00058312
00058313
00115413
00115414
00115415
Contained_in_operonCEOP2532
Ortholog (33)
Structured_descriptionConcise_descriptionB0491.7 encodes a putative diphthine synthase orthologous to S. cerevisiae DPH5; DPH5 is an S-adenosylmethionine:EF-2 methyltransferase required for the enzymatic conversion of 3-amino-3-carboxypropyl-histidine to diphthine; DPH5 adds at least the last two of the three methyl groups present in diphthine, and is homologous to bacterial AdoMet:uroporphyrinogen III methyltransferases.Paper_evidenceWBPaper00005654
WBPaper00012895
WBPaper00013419
WBPaper00013534
WBPaper00013537
WBPaper00013539
WBPaper00013556
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable diphthine synthase activity. Predicted to be involved in methylation and protein histidyl modification to diphthamide. Is an ortholog of human DPH5 (diphthamide biosynthesis 5).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070479Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:24270)
Molecular_infoCorresponding_CDSB0491.7
Corresponding_transcriptB0491.7.1
Other_sequence (38)
Associated_featureWBsf989723
WBsf989724
WBsf1013217
WBsf1013218
WBsf222128
Experimental_infoRNAi_resultWBRNAi00061719Inferred_automaticallyRNAi_primary
WBRNAi00039105Inferred_automaticallyRNAi_primary
WBRNAi00009805Inferred_automaticallyRNAi_primary
WBRNAi00028169Inferred_automaticallyRNAi_primary
Expr_patternExpr1026360
Expr1033100
Expr1143263
Expr2000207
Expr2018427
Drives_constructWBCnstr00033929
Construct_productWBCnstr00033929
Microarray_results (20)
Expression_cluster (112)
SAGE_tagSAGE:aatgcagttggctgttgStrandSense
Unambiguously_mapped
SAGE:tcgacttccaStrandAntisense
SAGE:ttggaaactttcaggccStrandSense
Unambiguously_mapped
SAGE:ttggaaacttStrandSense
Unambiguously_mapped
Interaction (88)
Map_infoMapIIPosition3.45336
PositivePositive_cloneB0491Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene