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WormBase Tree Display for Gene: WBGene00007993

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Name Class

WBGene00007993SMapS_parentSequenceC37E2
IdentityVersion2
NameCGC_nameidhb-1Person_evidenceWBPerson1983
WBPerson261
Sequence_nameC37E2.1
Molecular_nameC37E2.1
C37E2.1.1
CE08620
C37E2.1.2
Other_nameCELE_C37E2.1Accession_evidenceNDBBX284606
Public_nameidhb-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:48WBPerson1971EventImportedInitial conversion from CDS class of WS125
208 Dec 2011 12:14:43WBPerson2970Name_changeCGC_nameidhb-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classidhb
Allele (85)
StrainWBStrain00001632
WBStrain00003080
WBStrain00032521
RNASeq_FPKM (74)
GO_annotation (12)
Ortholog (37)
ParalogWBGene00009440Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00016266Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00009664Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionC37E2.1 encodes the C. elegans homolog of the beta subunit of an NAD+-dependent mitochondrial isocitrate dehydrogenase; by homology, the product of C37E2.1 is predicted to catalyze the formation of alpha-ketoglutarate from isocitrate as part of the citric acid cycle.Curator_confirmedWBPerson1843
Date_last_updated26 Oct 2011 00:00:00
Automated_descriptionPredicted to enable isocitrate dehydrogenase (NAD+) activity and metal ion binding activity. Predicted to be involved in isocitrate metabolic process and tricarboxylic acid cycle. Predicted to be located in mitochondrion. Expressed in head. Human ortholog(s) of this gene implicated in retinitis pigmentosa 46. Is an ortholog of human IDH3B (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0110409Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:5385)
Molecular_infoCorresponding_CDSC37E2.1
Corresponding_transcriptC37E2.1.1
C37E2.1.2
Other_sequence (88)
Associated_feature (12)
Experimental_infoRNAi_resultWBRNAi00093933Inferred_automaticallyRNAi_primary
WBRNAi00029640Inferred_automaticallyRNAi_primary
WBRNAi00070695Inferred_automaticallyRNAi_primary
WBRNAi00093903Inferred_automaticallyRNAi_primary
WBRNAi00011720Inferred_automaticallyRNAi_primary
WBRNAi00093973Inferred_automaticallyRNAi_primary
WBRNAi00070696Inferred_automaticallyRNAi_primary
WBRNAi00042113Inferred_automaticallyRNAi_primary
Expr_patternChronogram1762
Chronogram1864
Expr5463
Expr1011002
Expr1033477
Expr1146114
Expr2012672
Expr2030908
Drives_constructWBCnstr00002471
WBCnstr00004352
WBCnstr00033325
Construct_productWBCnstr00033325
Microarray_results (25)
Expression_cluster (147)
Interaction (71)
Map_infoMapXPosition16.6584
PositivePositive_cloneC37E2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027145
WBPaper00038491
WBPaper00049828
WBPaper00055090
WBPaper00065625
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene