WormBase Tree Display for Gene: WBGene00008387
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| WBGene00008387 | SMap | S_parent | Sequence | D1081 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | zhp-2 | Paper_evidence | WBPaper00053811 | |||||
| Sequence_name | D1081.9 | ||||||||
| Molecular_name | D1081.9 | ||||||||
| D1081.9.1 | |||||||||
| CE23619 | |||||||||
| Other_name | CELE_D1081.9 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | zhp-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:49 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 16 Apr 2018 13:37:57 | WBPerson1983 | Name_change | CGC_name | zhp-2 | ||||
| 3 | 24 May 2018 17:10:07 | WBPerson1983 | Name_change | CGC_name | zhp-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | zhp | ||||||||
| Allele (20) | |||||||||
| Strain | WBStrain00047221 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Contained_in_operon | CEOP1894 | ||||||||
| Ortholog (28) | |||||||||
| Paralog | WBGene00006976 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00012678 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00018867 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00011062 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| Structured_description | Concise_description | D1081.9 encodes a RING finger/coiled-coil protein homologous to budding yeast Cst9p/Zip3 (meiotically expressed) and human RNF212 (associated with varying recombination rate), RNF212B, and HEI10; D1081.9 is paralogous to F55A12.10, ZHP-3, and Y39B6A.16; D1081.9 is expressed during meiosis and required for normal levels of meiotic crossing-over; the protein physically interacts with F55A12.10, and localizes to the synaptonemal complex; together with ZHP-3 and Y39B6A.16, these proteins regulate meiotic recombination. | Paper_evidence | WBPaper00031553 | |||||
| WBPaper00053811 | |||||||||
| Person_evidence | WBPerson136 | ||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 15 Mar 2018 00:00:00 | ||||||||
| Automated_description | Predicted to enable SUMO transferase activity. Predicted to be involved in homologous chromosome pairing at meiosis and protein sumoylation. Predicted to be located in synaptonemal complex. Human ortholog(s) of this gene implicated in spermatogenic failure 62. Is an ortholog of human RNF212 (ring finger protein 212) and RNF212B (ring finger protein 212B). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0112351 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:27729) | ||||
| Molecular_info | Corresponding_CDS | D1081.9 | |||||||
| Corresponding_transcript | D1081.9.1 | ||||||||
| Other_sequence | CSC01520_1 | ||||||||
| CRC07217_1 | |||||||||
| CBC06493_1 | |||||||||
| FD517633.1 | |||||||||
| Associated_feature | WBsf1010244 | ||||||||
| WBsf219928 | |||||||||
| WBsf219929 | |||||||||
| WBsf219930 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00043418 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00116586 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00003274 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030364 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1029192 | ||||||||
| Expr1033635 | |||||||||
| Expr1147405 | |||||||||
| Expr2002049 | |||||||||
| Expr2020271 | |||||||||
| Drives_construct | WBCnstr00033004 | ||||||||
| Construct_product | WBCnstr00033004 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (138) | |||||||||
| Interaction | WBInteraction000547618 | ||||||||
| WBInteraction000547619 | |||||||||
| WBInteraction000548954 | |||||||||
| WBInteraction000556708 | |||||||||
| Map_info | Map | I | Position | 2.86059 | |||||
| Positive | Positive_clone | D1081 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00030887 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00053811 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
