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WormBase Tree Display for Gene: WBGene00008403

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Name Class

WBGene00008403SMapS_parentSequenceD2013
IdentityVersion2
NameCGC_namecsa-1Paper_evidenceWBPaper00046135
Person_evidenceWBPerson8633
Sequence_nameD2013.3
Molecular_nameD2013.3
D2013.3.1
CE17620
Other_nameCELE_D2013.3Accession_evidenceNDBBX284602
Public_namecsa-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:49WBPerson1971EventImportedInitial conversion from CDS class of WS125
229 Nov 2016 11:06:21WBPerson2970Name_changeCGC_namecsa-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcsa
Allele (29)
RNASeq_FPKM (74)
GO_annotation00062969
00062970
00062971
00062972
00062973
00062974
00116306
Ortholog (23)
ParalogWBGene00003036Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00004312Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00021899Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionAutomated_descriptionPredicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process; protein polyubiquitination; and transcription-coupled nucleotide-excision repair. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex and nucleotide-excision repair complex. Used to study Cockayne syndrome. Human ortholog(s) of this gene implicated in Cockayne syndrome A and UV-sensitive syndrome. Is an ortholog of human ERCC8 (ERCC excision repair 8, CSA ubiquitin ligase complex subunit).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:2962Homo sapiensPaper_evidenceWBPaper00046135
Accession_evidenceOMIM216400
614621
Curator_confirmedWBPerson324
Date_last_updated17 Jul 2015 00:00:00
Potential_modelDOID:2962Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3439)
DOID:0060240Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3439)
DOID:0080907Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:3439)
Models_disease_in_annotationWBDOannot00000358
Molecular_infoCorresponding_CDSD2013.3
Corresponding_transcriptD2013.3.1
Associated_featureWBsf650419
WBsf989025
WBsf1012841
WBsf223634
Experimental_infoRNAi_resultWBRNAi00012563Inferred_automaticallyRNAi_primary
WBRNAi00000789Inferred_automaticallyRNAi_primary
WBRNAi00043439Inferred_automaticallyRNAi_primary
WBRNAi00043440Inferred_automaticallyRNAi_primary
Expr_patternExpr1010291
Expr1033641
Expr1147436
Expr2010546
Expr2028786
Drives_constructWBCnstr00032989
Construct_productWBCnstr00032989
Microarray_results (18)
Expression_cluster (99)
InteractionWBInteraction000153156
WBInteraction000200409
WBInteraction000287513
WBInteraction000335464
WBInteraction000395045
WBInteraction000451549
Map_infoMapIIPosition1.12779
PositivePositive_cloneD2013Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00046135
WBPaper00053104
WBPaper00054563
WBPaper00060426
WBPaper00065149
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene