WormBase Tree Display for Gene: WBGene00008809
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| WBGene00008809 | SMap | S_parent | Sequence | F14F7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cyp-13A11 | |||||||
| Sequence_name | F14F7.2 | ||||||||
| Molecular_name | F14F7.2 | ||||||||
| F14F7.2.1 | |||||||||
| CE15822 | |||||||||
| Other_name | CELE_F14F7.2 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | cyp-13A11 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:49 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 21 Sep 2004 09:38:16 | WBPerson1971 | Name_change | CGC_name | cyp-13A11 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cyp | ||||||||
| Allele (60) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00030755 | ||||||||
| 00030756 | |||||||||
| 00030757 | |||||||||
| 00116653 | |||||||||
| 00116654 | |||||||||
| 00116655 | |||||||||
| 00116656 | |||||||||
| Ortholog (95) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | cyp-13A11 encodes one of ~80 C. elegans cytochrome P450s: membrane-associated, heme-containing NADPH-dependent monooxygenases that catalyze the oxidative metabolism of a variety of exogenous compounds and endogenous substrates; cyp-13A11 expression is upregulated in response to the tetrachlorobiphenyl PCB52. | Paper_evidence | WBPaper00029387 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 20 Nov 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable heme binding activity; iron ion binding activity; and oxidoreductase activity. Human ortholog(s) of this gene implicated in several diseases, including Ghosal hematodiaphyseal syndrome; familial Mediterranean fever; and leukemia (multiple). Is an ortholog of several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A5 (cytochrome P450 family 3 subfamily A member 5); and CYP3A7 (cytochrome P450 family 3 subfamily A member 7). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:8552 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||
| DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | ||||||
| DOID:2987 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | ||||||
| DOID:9952 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
| DOID:0112251 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:11609) | ||||||
| DOID:0080630 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
| DOID:10825 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2638) | ||||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2637) | ||||||
| Molecular_info | Corresponding_CDS | F14F7.2 | |||||||
| Corresponding_transcript | F14F7.2.1 | ||||||||
| Other_sequence | MHC11857_1 | ||||||||
| Dviv_isotig30531 | |||||||||
| MIC06204_1 | |||||||||
| PP00329 | |||||||||
| MH06251 | |||||||||
| Associated_feature | WBsf994784 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00092628 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00006998 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030954 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00114812 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00013294 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00044621 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00044622 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00006125 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1026363 | ||||||||
| Expr1148589 | |||||||||
| Expr2010679 | |||||||||
| Expr2028919 | |||||||||
| Drives_construct | WBCnstr00032668 | ||||||||
| Construct_product | WBCnstr00032668 | ||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (108) | |||||||||
| Interaction (25) | |||||||||
| Map_info | Map | III | Position | 20.7475 | |||||
| Positive | Positive_clone | F14F7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00029387 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00042257 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00064598 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| [200225 pad] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (20.7407) | |||||||||
| Method | Gene |
