WormBase Tree Display for Gene: WBGene00009178
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WBGene00009178 | SMap | S_parent | Sequence | CHROMOSOME_I | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | uggt-2 | Paper_evidence | WBPaper00040397 | |||
Person_evidence | WBPerson12962 | ||||||
Sequence_name | F26H9.8 | ||||||
Molecular_name | F26H9.8 | ||||||
F26H9.8.1 | |||||||
CE42103 | |||||||
Other_name | CELE_F26H9.8 | Accession_evidence | NDB | BX284601 | |||
Public_name | uggt-2 | ||||||
DB_info | Database | AceView | gene | 1J903 | |||
WormQTL | gene | WBGene00009178 | |||||
WormFlux | gene | WBGene00009178 | |||||
NDB | locus_tag | CELE_F26H9.8 | |||||
Panther | gene | CAEEL|WormBase=WBGene00009178|UniProtKB=G5EF14 | |||||
family | PTHR11226 | ||||||
NCBI | gene | 172758 | |||||
RefSeq | protein | NM_060083.5 | |||||
TREEFAM | TREEFAM_ID | TF300320 | |||||
TrEMBL | UniProtAcc | G5EF14 | |||||
UniProt_GCRP | UniProtAcc | G5EF14 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | uggt | ||||||
Allele (96) | |||||||
Strain | WBStrain00036995 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (19) | |||||||
Ortholog (56) | |||||||
Paralog | WBGene00018604 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Panther | |||||||
WormBase-Compara | |||||||
Structured_description | Concise_description | uggt-2 encodes one of two C. elegans homologs of UDP-Glc:glycoprotein glucosyltransferase (UGGT), an endoplasmic reticulum enzyme involved in quality control of glycoprotein folding; loss of uggt-2 activity via RNAi indicates that uggt-2 is an essential embryonic gene that is also required for regulating the rate of larval developmental; uggt-2 interacts genetically with ire-1 with respect to basal unfolded protein response during larval development; uggt-2 is expressed throughout larval development, with peak levels seen at the L2/L3 stages. | Paper_evidence | WBPaper00040397 | |||
Curator_confirmed | WBPerson1843 | ||||||
Date_last_updated | 14 Nov 2011 00:00:00 | ||||||
Automated_description | Predicted to enable UDP-glucose:glycoprotein glucosyltransferase activity and unfolded protein binding activity. Involved in IRE1-mediated unfolded protein response; regulation of embryonic development; and regulation of nematode larval development. Predicted to be located in endoplasmic reticulum. Is an ortholog of human UGGT1 (UDP-glucose glycoprotein glucosyltransferase 1) and UGGT2 (UDP-glucose glycoprotein glucosyltransferase 2). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F26H9.8 | |||||
Corresponding_CDS_history | F26H9.8:wp187 | ||||||
Corresponding_transcript | F26H9.8.1 | ||||||
Other_sequence | MAC00138_2 | ||||||
Name_isotig04816 | |||||||
MA00557 | |||||||
MIC03277_1 | |||||||
Associated_feature | WBsf656708 | ||||||
WBsf218269 | |||||||
Experimental_info | RNAi_result (14) | ||||||
Expr_pattern | Expr9682 | ||||||
Expr1010326 | |||||||
Expr1149623 | |||||||
Expr2017753 | |||||||
Expr2035892 | |||||||
Drives_construct | WBCnstr00032396 | ||||||
Construct_product | WBCnstr00032396 | ||||||
Microarray_results (19) | |||||||
Expression_cluster (137) | |||||||
Interaction (20) | |||||||
Map_info | Map | I | Position | 3.74311 | |||
Positive | Positive_clone | F26H9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00029024 | ||||||
WBPaper00038491 | |||||||
WBPaper00039794 | |||||||
WBPaper00040397 | |||||||
WBPaper00042697 | |||||||
WBPaper00055090 | |||||||
WBPaper00060116 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |