WormBase Tree Display for Gene: WBGene00009385
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| WBGene00009385 | SMap | S_parent | Sequence | F35B12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | sas-5 | Person_evidence | WBPerson561 | |||||
| Sequence_name | F35B12.5 | ||||||||
| Molecular_name | F35B12.5a | ||||||||
| F35B12.5a.1 | |||||||||
| CE27758 | |||||||||
| F35B12.5c | |||||||||
| CE05804 | |||||||||
| F35B12.5b | |||||||||
| F35B12.5c.1 | |||||||||
| Other_name | CELE_F35B12.5 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | sas-5 | ||||||||
| DB_info | Database | AceView | gene | 5M91 | |||||
| WormQTL | gene | WBGene00009385 | |||||||
| WormFlux | gene | WBGene00009385 | |||||||
| NDB | locus_tag | CELE_F35B12.5 | |||||||
| NCBI | gene | 179592 | |||||||
| RefSeq | protein | NR_069564.1 | |||||||
| NM_001269409.3 | |||||||||
| NM_001269410.3 | |||||||||
| SwissProt | UniProtAcc | Q20010 | |||||||
| TREEFAM | TREEFAM_ID | TF320227 | |||||||
| UniProt_GCRP | UniProtAcc | Q20010 | |||||||
| RNAcentral | URSid | URS0000141765 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:50 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 02 Jul 2004 16:58:07 | WBPerson1971 | Name_change | CGC_name | sas-5 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sas | ||||||||
| Allele (41) | |||||||||
| Strain | WBStrain00036196 | ||||||||
| WBStrain00008276 | |||||||||
| WBStrain00037863 | |||||||||
| WBStrain00034770 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (18) | |||||||||
| Ortholog (21) | |||||||||
| Structured_description | Concise_description | sas-5 encodes a coiled-coil protein whose activity is required, paternally, maternally, and in a dose-dependent manner, for daughter centriole formation; SAS-5 localizes to both the cytoplasm and to centrioles, and photobleaching experiments reveal rapid SAS-5 cycling between these two cellular components throughout the cell cycle; SAS-5 localization to centrioles depends upon the ZYG-1 kinase and the SAS-6 coiled-coil protein, two proteins also required for centriole duplication; in turn, SAS-5 activity is required for SAS-6 centriolar localization, as SAS-6 fails to localize properly in sas-5 mutant embryos; SAS-5 and SAS-6 physically interact. | Paper_evidence | WBPaper00024227 | |||||
| WBPaper00024912 | |||||||||
| WBPaper00038324 | |||||||||
| WBPaper00041634 | |||||||||
| Curator_confirmed | WBPerson12884 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 29 Nov 2012 00:00:00 | ||||||||
| Automated_description | Involved in centriole replication. Located in centriole and cytoplasm. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F35B12.5a | |||||||
| F35B12.5c | |||||||||
| Corresponding_CDS_history | F35B12.5:wp51 | ||||||||
| Corresponding_transcript | F35B12.5b | ||||||||
| F35B12.5a.1 | |||||||||
| F35B12.5c.1 | |||||||||
| Other_sequence | EY461470.1 | ||||||||
| CR00869 | |||||||||
| ACC38313_1 | |||||||||
| FD515929.1 | |||||||||
| CSC00624_1 | |||||||||
| CR06286 | |||||||||
| CBC06153_1 | |||||||||
| CR01653 | |||||||||
| CRC05520_1 | |||||||||
| Associated_feature | WBsf647279 | ||||||||
| WBsf977294 | |||||||||
| WBsf977295 | |||||||||
| WBsf1001393 | |||||||||
| WBsf1020475 | |||||||||
| WBsf232527 | |||||||||
| WBsf232528 | |||||||||
| Experimental_info | RNAi_result (34) | ||||||||
| Expr_pattern | Expr3402 | ||||||||
| Expr3663 | |||||||||
| Expr9693 | |||||||||
| Expr1016438 | |||||||||
| Expr1034111 | |||||||||
| Expr1150165 | |||||||||
| Expr1200220 | |||||||||
| Expr2015602 | |||||||||
| Expr2033837 | |||||||||
| Drives_construct | WBCnstr00019931 | ||||||||
| WBCnstr00032231 | |||||||||
| Construct_product | WBCnstr00011380 | ||||||||
| WBCnstr00011581 | |||||||||
| WBCnstr00015887 | |||||||||
| WBCnstr00019931 | |||||||||
| WBCnstr00020574 | |||||||||
| WBCnstr00020575 | |||||||||
| WBCnstr00032231 | |||||||||
| Antibody | WBAntibody00000749 | ||||||||
| WBAntibody00000819 | |||||||||
| WBAntibody00000820 | |||||||||
| WBAntibody00002240 | |||||||||
| WBAntibody00003027 | |||||||||
| WBAntibody00003042 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (175) | |||||||||
| Interaction (80) | |||||||||
| Map_info | Map | V | Position | 3.21148 | Error | 0.001438 | |||
| Positive | Positive_clone | F35B12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5449 | |||||||
| Pseudo_map_position | |||||||||
| Reference (42) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
