WormBase Tree Display for Gene: WBGene00010485
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| WBGene00010485 | SMap | S_parent | Sequence | K01H12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | ant-1.3 | Paper_evidence | WBPaper00031899 | |||||
| Person_evidence | WBPerson1746 | ||||||||
| Sequence_name | K01H12.2 | ||||||||
| Molecular_name | K01H12.2 | ||||||||
| K01H12.2.1 | |||||||||
| CE03454 | |||||||||
| Other_name | wan-4 | Paper_evidence | WBPaper00033159 | ||||||
| CELE_K01H12.2 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | ant-1.3 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:51 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 04 Jun 2008 11:48:40 | WBPerson2970 | Name_change | CGC_name | ant-1.3 | ||||
| 3 | 03 Mar 2014 14:12:13 | WBPerson2970 | Name_change | Other_name | wan-4 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ant | ||||||||
| Allele (24) | |||||||||
| Strain | WBStrain00032422 | ||||||||
| WBStrain00036533 | |||||||||
| WBStrain00036577 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (62) | |||||||||
| Paralog (35) | |||||||||
| Structured_description | Concise_description | ant-1.3 encodes an ortholog of the human adenine nucleotide translocase ANT genes, the other ANT genes in C. elegans include ant-1.1, ant-1.2 and ant-1.4; by homology, ANT-1.3 is predicted to mediate the exchange of ATP generated in the mitochondria for cytosolic ADP; ANT-1.3 GFP fusion protein is expressed in the intestine and the anterior of the elongating embryo, and in a pair of head neurons and a ventral neuron in the larval and adult stages. | Paper_evidence | WBPaper00031899 | |||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 25 Apr 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable adenine nucleotide transmembrane transporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrial inner membrane. Expressed in VA11 and intestine. Human ortholog(s) of this gene implicated in Alzheimer's disease; autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2; facioscapulohumeral muscular dystrophy; intrinsic cardiomyopathy (multiple); and mitochondrial DNA depletion syndrome (multiple). Is an ortholog of human SLC25A5 (solute carrier family 25 member 5) and SLC25A6 (solute carrier family 25 member 6). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10990) | ||||
| DOID:0110429 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10990) | ||||||
| DOID:0080335 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10990) | ||||||
| DOID:699 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10990) | ||||||
| DOID:11984 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10990) | ||||||
| DOID:11727 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10990) | ||||||
| DOID:0111517 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10990) | ||||||
| DOID:12558 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10990) | ||||||
| DOID:0080130 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10990) | ||||||
| Molecular_info | Corresponding_CDS | K01H12.2 | |||||||
| Corresponding_transcript | K01H12.2.1 | ||||||||
| Other_sequence (209) | |||||||||
| Associated_feature | WBsf230605 | ||||||||
| Experimental_info | RNAi_result (14) | ||||||||
| Expr_pattern | Expr8110 | ||||||||
| Expr1017297 | |||||||||
| Expr1034579 | |||||||||
| Expr1153369 | |||||||||
| Expr2009345 | |||||||||
| Expr2027581 | |||||||||
| Drives_construct | WBCnstr00013118 | ||||||||
| WBCnstr00031385 | |||||||||
| Construct_product | WBCnstr00013118 | ||||||||
| WBCnstr00031385 | |||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (242) | |||||||||
| Interaction (117) | |||||||||
| Map_info | Map | IV | Position | 4.3819 | Error | 0.001189 | |||
| Positive | Positive_clone | K01H12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00031899 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00062518 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
