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WormBase Tree Display for Gene: WBGene00010872

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Name Class

WBGene00010872SMapS_parentSequenceM05B5
IdentityVersion2
NameCGC_nameplag-15Person_evidenceWBPerson3997
Sequence_nameM05B5.4
Molecular_nameM05B5.4
M05B5.4.1
CE06190
Other_namelpla-2Paper_evidenceWBPaper00061595
Curator_confirmedWBPerson21950
CELE_M05B5.4Accession_evidenceNDBBX284601
Public_nameplag-15
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
209 Dec 2021 11:50:30WBPerson1983Name_changeCGC_nameplag-15
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classplag
Allele (23)
RNASeq_FPKM (74)
GO_annotation00071987
00118196
00118197
Ortholog (44)
Structured_descriptionConcise_descriptionThe M05B5.4 gene encodes an ortholog of the human gene LECITHIN-CHOLESTEROL ACYLTRANSFERASE (LCAT; OMIM:606967), which when mutated leads to lecithin-cholesterol acyltransferase deficiency (OMIM:245900).Paper_evidenceWBPaper00004637
Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable O-acyltransferase activity. Predicted to be involved in lipid metabolic process. Expressed in hypodermis; intestine; neuronal sheath cell; pharynx; and tail. Human ortholog(s) of this gene implicated in Norum disease and arteriosclerosis. Is an ortholog of human PLA2G15 (phospholipase A2 group XV).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:1391Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6522)
DOID:2349Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6522)
Molecular_infoCorresponding_CDSM05B5.4
Corresponding_transcriptM05B5.4.1
Other_sequence (31)
Associated_featureWBsf643430
WBsf643431
WBsf656488
WBsf984119
WBsf1010046
WBsf217962
Experimental_infoRNAi_resultWBRNAi00023279Inferred_automaticallyRNAi_primary
WBRNAi00114805Inferred_automaticallyRNAi_primary
WBRNAi00004041Inferred_automaticallyRNAi_primary
WBRNAi00024077Inferred_automaticallyRNAi_primary
WBRNAi00023790Inferred_automaticallyRNAi_primary
WBRNAi00023542Inferred_automaticallyRNAi_primary
WBRNAi00116533Inferred_automaticallyRNAi_primary
WBRNAi00050928Inferred_automaticallyRNAi_primary
Expr_patternExpr4067
Expr15998
Expr15999
Expr1013497
Expr1034765
Expr1154624
Expr2005215
Expr2023433
Drives_constructWBCnstr00031093
WBCnstr00042658
Construct_productWBCnstr00031093
WBCnstr00042658
Microarray_results (20)
Expression_cluster (147)
Interaction (18)
Map_infoMapIPosition1.83191
PositivePositive_cloneM05B5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00029387
WBPaper00038491
WBPaper00042257
WBPaper00055090
WBPaper00059755
WBPaper00061595
WBPaper00064339
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene