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WormBase Tree Display for Gene: WBGene00011004

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Name Class

WBGene00011004SMapS_parentSequenceR04B5
IdentityVersion1
NameSequence_nameR04B5.6
Molecular_nameR04B5.6
R04B5.6.1
CE06216
Other_nameCELE_R04B5.6Accession_evidenceNDBBX284605
Public_nameR04B5.6
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:52WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (30)
RNASeq_FPKM (74)
GO_annotation00072477
00072478
00072479
00072480
00118319
Ortholog (41)
Paralog (11)
Structured_descriptionConcise_descriptionR04B5.6 encodes one of two C. elegans sorbitol dehydrogense orthologs; by homology the product of R04B5.6 is predicted to catalyze the reversible oxidation of sorbitol to fructose in the presence of NAD+; in the embryo, an R04B5.6::gfp fusion is expressed in pharyngeal cells and head neurons.Paper_evidenceWBPaper00031003
Curator_confirmedWBPerson1843
Date_last_updated17 Nov 2008 00:00:00
Automated_descriptionPredicted to enable L-iditol 2-dehydrogenase activity. Predicted to be involved in sorbitol catabolic process. Expressed in head neurons and pharyngeal cell. Human ortholog(s) of this gene implicated in sorbitol dehydrogenase deficiency with peripheral neuropathy. Is an ortholog of human SORD (sorbitol dehydrogenase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0081376Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11184)
Molecular_infoCorresponding_CDSR04B5.6
Corresponding_transcriptR04B5.6.1
Other_sequence (41)
Associated_featureWBsf647130
WBsf661609
WBsf661610
WBsf232325
WBsf232326
WBsf232327
Experimental_infoRNAi_resultWBRNAi00034578Inferred_automaticallyRNAi_primary
WBRNAi00051227Inferred_automaticallyRNAi_primary
WBRNAi00051228Inferred_automaticallyRNAi_primary
WBRNAi00017395Inferred_automaticallyRNAi_primary
Expr_patternExpr4947
Expr1029074
Expr1034824
Expr1154932
Expr2005366
Expr2023587
Drives_constructWBCnstr00012360
WBCnstr00031000
Construct_productWBCnstr00031000
Microarray_results (17)
Expression_cluster (135)
Interaction (28)
Map_infoPositivePositive_cloneR04B5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionV2.27361
ReferenceWBPaper00031003
WBPaper00038491
WBPaper00055090
MethodGene