WormBase Tree Display for Gene: WBGene00011698

WBGene00011698 SMap: S_parent: Sequence: T10H4
  Identity: Version: 2
    Name: CGC_name: cyp-34A1
      Sequence_name: T10H4.10
      Molecular_name: T10H4.10
        T10H4.10.1
        CE16395
      Other_name: CELE_T10H4.10 Accession_evidence: NDB BX284605
      Public_name: cyp-34A1
    DB_info: Database: AceView gene 5P762
        WormQTL gene WBGene00011698
        WormFlux gene WBGene00011698
        NDB locus_tag CELE_T10H4.10
        Panther gene CAEEL|WormBase=WBGene00011698|UniProtKB=O62378
          family PTHR24300
        NCBI gene 188399
        RefSeq protein NM_074386.2
        TrEMBL UniProtAcc O62378
        UniProt_GCRP UniProtAcc O62378
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:52 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 21 Sep 2004 09:38:16 WBPerson1971 Name_change: CGC_name: cyp-34A1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cyp
    Allele (141)
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (154)
    Paralog (44)
    Structured_description: Automated_description: Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including autoimmune hepatitis; hematologic cancer (multiple); and rhinitis. Is an ortholog of several human genes including CYP2D6 (cytochrome P450 family 2 subfamily D member 6); CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); and CYP2F1 (cytochrome P450 family 2 subfamily F member 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (11)
  Molecular_info: Corresponding_CDS: T10H4.10
    Corresponding_transcript: T10H4.10.1
    Other_sequence: PPC13524_1
      PPC18551_1
      CJC14248_1
      Tcol_isotig13378
    Associated_feature: WBsf653440
      WBsf668687
      WBsf235043
      WBsf235044
  Experimental_info: RNAi_result: WBRNAi00053073 Inferred_automatically: RNAi_primary
      WBRNAi00092671 Inferred_automatically: RNAi_primary
      WBRNAi00018563 Inferred_automatically: RNAi_primary
      WBRNAi00035453 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1023825
      Expr1156682
      Expr2010726
      Expr2028964
    Drives_construct: WBCnstr00030460
    Construct_product: WBCnstr00030460
    Microarray_results (17)
    Expression_cluster (89)
    Interaction: WBInteraction000175689
      WBInteraction000291959
      WBInteraction000313295
      WBInteraction000334521
      WBInteraction000385894
      WBInteraction000385895
      WBInteraction000406987
      WBInteraction000447574
      WBInteraction000468953
  Map_info: Map: V Position: 7.65831 Error: 0.000811
    Positive: Positive_clone: T10H4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00064093
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene