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WormBase Tree Display for Gene: WBGene00011897

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Name Class

WBGene00011897SMapS_parentSequenceT21C9
IdentityVersion2
NameCGC_namescpl-4Person_evidenceWBPerson56
Sequence_nameT21C9.12
Molecular_nameT21C9.12a
T21C9.12a.1
CE06481
T21C9.12b
CE53110
T21C9.12b.1
Other_nameCELE_T21C9.12Accession_evidenceNDBBX284605
Public_namescpl-4
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:53WBPerson1971EventImportedInitial conversion from CDS class of WS125
202 Feb 2007 10:20:45WBPerson2970Name_changeCGC_namescpl-4
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classscpl
Allele (35)
RNASeq_FPKM (74)
GO_annotation (11)
Contained_in_operonCEOP5530
Ortholog (38)
ParalogWBGene00007054Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00018474Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00021629Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionscpl-4 encodes an ortholog of budding yeast TIM50 and human TIMM50(OMIM:607381); by orthology, SCPL-4 is expected to be part of themitochondrial inner membrane protein translocase; SCPL-4 is required forembryonic development and fertility in mass RNAi assays; SCPL-4 isdistantly similar to FCP-1 and SCPL-1, -2, and -3.Paper_evidenceWBPaper00024497
WBPaper00025054
WBPaper00029275
WBPaper00029276
Curator_confirmedWBPerson567
Date_last_updated25 Apr 2007 00:00:00
Automated_descriptionPredicted to be involved in protein import into mitochondrial matrix. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 9. Is an ortholog of human TIMM50 (translocase of inner mitochondrial membrane 50).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070002Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:23656)
Molecular_infoCorresponding_CDST21C9.12a
T21C9.12b
Corresponding_transcriptT21C9.12a.1
T21C9.12b.1
Other_sequence (33)
Associated_featureWBsf647179
WBsf661646
WBsf661647
WBsf232403
WBsf232404
Experimental_infoRNAi_resultWBRNAi00093682Inferred_automaticallyRNAi_primary
WBRNAi00053716Inferred_automaticallyRNAi_primary
WBRNAi00110746Inferred_automaticallyRNAi_primary
WBRNAi00106908Inferred_automaticallyRNAi_primary
WBRNAi00035750Inferred_automaticallyRNAi_primary
WBRNAi00095734Inferred_automaticallyRNAi_primary
Expr_patternExpr1021209
Expr1035246
Expr1157266
Expr2015649
Expr2033881
Drives_constructWBCnstr00030301
Construct_productWBCnstr00030301
AntibodyWBAntibody00003018
Microarray_results (21)
Expression_cluster (122)
Interaction (48)
Map_infoMapVPosition2.60665Error0.00121
PositivePositive_cloneT21C9Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00029277
WBPaper00031595
WBPaper00038491
WBPaper00049490
WBPaper00049828
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene