WormBase Tree Display for Gene: WBGene00012193

WBGene00012193 SMap: S_parent: Sequence: W02A11
  Identity: Version: 2
    Name: CGC_name: vps-25 Person_evidence: WBPerson3188
      Sequence_name: W02A11.2
      Molecular_name: W02A11.2
        W02A11.2.1
        CE24025
        W02A11.2.2
      Other_name: CELE_W02A11.2 Accession_evidence: NDB BX284601
      Public_name: vps-25
    DB_info: Database: AceView gene 1N326
        WormQTL gene WBGene00012193
        WormFlux gene WBGene00012193
        NDB locus_tag CELE_W02A11.2
        Panther gene CAEEL|WormBase=WBGene00012193|UniProtKB=Q9U354
          family PTHR13149
        NCBI gene 173143
        RefSeq protein NM_001392958.1
        TREEFAM TREEFAM_ID TF317731
        TrEMBL UniProtAcc Q9U354
        UniProt_GCRP UniProtAcc Q9U354
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:53 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 02 Mar 2009 17:16:53 WBPerson9133 Name_change: CGC_name: vps-25
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: vps
    Allele (171)
    Strain: WBStrain00055449
    RNASeq_FPKM (74)
    GO_annotation: 00099952
      00099953
      00099954
      00099955
      00099956
      00119369
      00119370
    Contained_in_operon: CEOP1676
    Ortholog (31)
    Structured_description: Concise_description: W02A11.2 encodes the C. elegans ortholog of the vacuolar protein sorting protein EAP20/VPS25; by homology, the product of W02A11.2 is predicted to be a component of ESCRT-II (Endosomal Sorting Complex Required for Transport) and function in endosomal trafficking. Paper_evidence: WBPaper00026641
          Curator_confirmed: WBPerson1843
          Date_last_updated: 01 Aug 2007 00:00:00
      Automated_description: Predicted to enable protein homodimerization activity and structural molecule activity. Predicted to be involved in protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be part of ESCRT II complex. Expressed in body wall musculature; pharyngeal muscle cell; and vulval muscle. Is an ortholog of human VPS25 (vacuolar protein sorting 25 homolog). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: W02A11.2
    Corresponding_transcript: W02A11.2.1
      W02A11.2.2
    Other_sequence (32)
    Associated_feature (12)
  Experimental_info: RNAi_result: WBRNAi00075860 Inferred_automatically: RNAi_primary
      WBRNAi00078463 Inferred_automatically: RNAi_primary
      WBRNAi00036157 Inferred_automatically: RNAi_primary
      WBRNAi00054538 Inferred_automatically: RNAi_primary
      WBRNAi00004363 Inferred_automatically: RNAi_primary
      WBRNAi00116516 Inferred_automatically: RNAi_primary
      WBRNAi00067368 Inferred_automatically: RNAi_primary
      WBRNAi00092991 Inferred_automatically: RNAi_primary
      WBRNAi00067252 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr12776
      Expr12780
      Expr1016764
      Expr1035392
      Expr1158084
      Expr2018016
      Expr2036153
    Drives_construct: WBCnstr00022876
    Construct_product: WBCnstr00022876
    Microarray_results (20)
    Expression_cluster (96)
    Interaction (26)
  Map_info: Map: I Position: 13.9637 Error: 0.001886
    Positive: Positive_clone: W02A11 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00026641
    WBPaper00030887
    WBPaper00036963
    WBPaper00038491
    WBPaper00038585
    WBPaper00039823
    WBPaper00040674
    WBPaper00055090
    WBPaper00064339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene