WormBase Tree Display for Gene: WBGene00012629

WBGene00012629 SMap: S_parent: Sequence: Y38H6C
  Identity: Version: 2
    Name: CGC_name: slc-36.3 Person_evidence: WBPerson260
      Sequence_name: Y38H6C.17
      Molecular_name: Y38H6C.17
        Y38H6C.17.1
        CE39824
      Other_name: CELE_Y38H6C.17 Accession_evidence: NDB BX284605
      Public_name: slc-36.3
    DB_info: Database: AceView gene 5V8
        WormQTL gene WBGene00012629
        WormFlux gene WBGene00012629
        NDB locus_tag CELE_Y38H6C.17
        Panther gene CAEEL|WormBase=WBGene00012629|UniProtKB=Q9XX44
          family PTHR22950
        NCBI gene 189698
        RefSeq protein NM_075559.7
        TrEMBL UniProtAcc Q9XX44
        UniProt_GCRP UniProtAcc Q9XX44
        OMIM gene 608331
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 29 Apr 2015 12:07:40 WBPerson2970 Name_change: CGC_name: slc-36.3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: slc
    Allele (135)
    Strain: WBStrain00037137
      WBStrain00037188
    RNASeq_FPKM (74)
    GO_annotation: 00104120
      00104121
      00104122
      00104123
      00104124
    Ortholog (38)
    Paralog (14)
    Structured_description: Concise_description: Y38H6C.17 encodes a putative amino acid transporter orthologous to human SLC36A1; Y38H6C.17 inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51; Y38H6C.17 has 11 predicted transmembrane alpha-helices; Y38H6C.17 has multiple C. elegans paralogs and additional non-nematode orthologs, including budding yeast AVT3 and AVT4. Paper_evidence: WBPaper00023909
            WBPaper00029271
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 15 Apr 2015 00:00:00
      Automated_description: Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be located in vacuolar membrane. Human ortholog(s) of this gene implicated in iminoglycinuria. Is an ortholog of several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A4 (solute carrier family 36 member 4). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0112265 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:18762)
  Molecular_info: Corresponding_CDS: Y38H6C.17
    Corresponding_CDS_history: Y38H6C.17:wp154
    Corresponding_transcript: Y38H6C.17.1
    Associated_feature: WBsf235232
  Experimental_info: RNAi_result: WBRNAi00020319 Inferred_automatically: RNAi_primary
      WBRNAi00064207 Inferred_automatically: RNAi_primary
      WBRNAi00056068 Inferred_automatically: RNAi_primary
      WBRNAi00064181 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1010871
      Expr1035580
      Expr1159591
      Expr2015876
      Expr2034109
    Drives_construct: WBCnstr00029876
    Construct_product: WBCnstr00029876
    Microarray_results (16)
    Expression_cluster (122)
  Map_info: Map: V Position: 25.011
    Positive: Positive_clone: Y38H6C Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene