WormBase Tree Display for Gene: WBGene00013441
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WBGene00013441 | SMap | S_parent | Sequence | Y66D12A | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | xpb-1 | Paper_evidence | WBPaper00037879 | |||||
Sequence_name | Y66D12A.15 | ||||||||
Molecular_name | Y66D12A.15 | ||||||||
Y66D12A.15.1 | |||||||||
CE28998 | |||||||||
Other_name | CELE_Y66D12A.15 | Accession_evidence | NDB | BX284603 | |||||
Public_name | xpb-1 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 26 May 2004 16:54:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
2 | 21 Jul 2014 15:41:21 | WBPerson2970 | Name_change | CGC_name | xpb-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | xpb | ||||||||
Allele (197) | |||||||||
Strain | WBStrain00002842 | ||||||||
WBStrain00051216 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (15) | |||||||||
Contained_in_operon | CEOP3885 | ||||||||
Ortholog (34) | |||||||||
Structured_description | Concise_description | Y66D12A.15 is orthologous to the human gene EXCISION REPAIR CROSS-COMPLEMENTING RODENT REPAIR DEFICIENCY, COMPLEMENTATION GROUP 3 (XERODERMA PIGMENTOSUM GROUP B COMPLEMENTING) (ERCC3; OMIM:133510), which when mutated leads to disease. | Curator_confirmed | WBPerson1823 | |||||
WBPerson567 | |||||||||
Date_last_updated | 06 Aug 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable 3'-5' DNA helicase activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to be part of nucleotide-excision repair factor 3 complex; transcription factor TFIIH holo complex; and transcription preinitiation complex. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; photosensitive trichothiodystrophy 2; and xeroderma pigmentosum group B. Is an ortholog of human ERCC3 (ERCC excision repair 3, TFIIH core complex helicase subunit). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3435) | ||||
DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3435) | ||||||
DOID:0110850 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3435) | ||||||
DOID:3908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3435) | ||||||
DOID:14250 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3435) | ||||||
DOID:0111866 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3435) | ||||||
DOID:0111869 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3435) | ||||||
DOID:0050427 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:3435) | ||||||
Molecular_info | Corresponding_CDS | Y66D12A.15 | |||||||
Corresponding_CDS_history | Y66D12A.15:wp61 | ||||||||
Corresponding_transcript | Y66D12A.15.1 | ||||||||
Other_sequence (97) | |||||||||
Associated_feature | WBsf658536 | ||||||||
WBsf994413 | |||||||||
WBsf225831 | |||||||||
WBsf225832 | |||||||||
Experimental_info | RNAi_result | WBRNAi00098251 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00075604 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00098245 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00098247 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00057939 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00098246 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Chronogram1104 | ||||||||
Expr1013919 | |||||||||
Expr1036007 | |||||||||
Expr1161369 | |||||||||
Expr2018101 | |||||||||
Expr2036239 | |||||||||
Drives_construct | WBCnstr00003364 | ||||||||
Microarray_results (17) | |||||||||
Expression_cluster (64) | |||||||||
Interaction (126) | |||||||||
Map_info | Map | III | Position | 10.7822 | |||||
Positive | Positive_clone | Y66D12A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00027223 | ||||||||
WBPaper00029038 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00060873 | |||||||||
WBPaper00062203 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |