WormBase Tree Display for Gene: WBGene00013443
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| WBGene00013443 | SMap | S_parent | Sequence | Y66D12A | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | such-1 | Paper_evidence | WBPaper00029006 | |||||
| Person_evidence | WBPerson533 | ||||||||
| Sequence_name | Y66D12A.17 | ||||||||
| Molecular_name | Y66D12A.17 | ||||||||
| Y66D12A.17.1 | |||||||||
| CE41524 | |||||||||
| Other_name | som-2 | Person_evidence | WBPerson205 | ||||||
| CELE_Y66D12A.17 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | such-1 | ||||||||
| DB_info | Database | AceView | gene | 3M604 | |||||
| WormQTL | gene | WBGene00013443 | |||||||
| WormFlux | gene | WBGene00013443 | |||||||
| NDB | locus_tag | CELE_Y66D12A.17 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00013443|UniProtKB=Q95Q00 | |||||||
| family | PTHR12830 | ||||||||
| NCBI | gene | 176583 | |||||||
| RefSeq | protein | NM_067084.7 | |||||||
| SwissProt | UniProtAcc | Q95Q00 | |||||||
| TREEFAM | TREEFAM_ID | TF105444 | |||||||
| UniProt_GCRP | UniProtAcc | Q95Q00 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 02 Feb 2007 17:11:41 | WBPerson2970 | Name_change | CGC_name | such-1 | ||||
| 3 | 25 Sep 2013 09:44:26 | WBPerson2970 | Event | Acquires_merge | WBGene00050979 | ||||
| Name_change | Other_name | som-2 | |||||||
| Acquires_merge | WBGene00050979 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | such | ||||||||
| Allele (239) | |||||||||
| Strain | WBStrain00023979 | ||||||||
| WBStrain00022410 | |||||||||
| WBStrain00022422 | |||||||||
| WBStrain00051670 | |||||||||
| WBStrain00051680 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00088067 | ||||||||
| 00088068 | |||||||||
| 00088069 | |||||||||
| 00088070 | |||||||||
| 00088071 | |||||||||
| 00088072 | |||||||||
| 00088073 | |||||||||
| 00088074 | |||||||||
| 00120294 | |||||||||
| Ortholog (26) | |||||||||
| Paralog | WBGene00001583 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | such-1 encodes a component of the anaphase promoting complex/cyclosome (APC/C), and is orthologous to human ANAPC5 and paralogous to GFI-3; such-1 helps enforce the spindle assembly checkpoint of the metaphase-to-anaphase transition during mitosis, and is required redundantly with gfi-3 for meiotic divisions; co-depletion of such-1 and gfi-3 results in meiotic arrest; in such-1(h1960) mutants, anaphase onset (and mitosis generally) is delayed in both germline and early embryonic mitosis, and X chromosome missegregation is increased; the long-term sterility (over two to three generations) of homozygous MAD1/mdf-1(gk2) mutations as well as X chromosome missegregation is suppressed by such-1(h1960); absence of centrioles and paternal DNA in a fraction of such-1(t1668) sperm causes paternal effect lethality in fertilised embryos. | Paper_evidence | WBPaper00005096 | |||||
| WBPaper00013611 | |||||||||
| WBPaper00029006 | |||||||||
| WBPaper00037650 | |||||||||
| WBPaper00037671 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 21 Sep 2015 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; and protein K11-linked ubiquitination. Predicted to be part of anaphase-promoting complex. Expressed in germ line; head neurons; sperm; and vulval precursor cell. Is an ortholog of human ANAPC5 (anaphase promoting complex subunit 5). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y66D12A.17 | |||||||
| Corresponding_CDS_history | Y66D12A.17:wp180 | ||||||||
| Corresponding_transcript | Y66D12A.17.1 | ||||||||
| Other_sequence (15) | |||||||||
| Associated_feature | WBsf651513 | ||||||||
| WBsf667449 | |||||||||
| WBsf994408 | |||||||||
| WBsf994409 | |||||||||
| WBsf994410 | |||||||||
| WBsf1016019 | |||||||||
| WBsf1016020 | |||||||||
| WBsf1016021 | |||||||||
| WBsf227585 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00057941 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00001568 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr9272 | ||||||||
| Expr1018287 | |||||||||
| Expr1036009 | |||||||||
| Expr1161371 | |||||||||
| Expr2017102 | |||||||||
| Expr2035238 | |||||||||
| Drives_construct | WBCnstr00007685 | ||||||||
| WBCnstr00013868 | |||||||||
| Microarray_results (16) | |||||||||
| Expression_cluster (120) | |||||||||
| Interaction (41) | |||||||||
| Map_info | Map | III | Position | 10.7335 | Error | 0.085723 | |||
| Positive | Positive_clone | Y66D12A | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00029006 | ||||||||
| WBPaper00033567 | |||||||||
| WBPaper00036784 | |||||||||
| WBPaper00037650 | |||||||||
| WBPaper00037671 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
