WormBase Tree Display for Gene: WBGene00013985
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| WBGene00013985 | SMap | S_parent | Sequence | ZK512 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | sec-16A.1 | Person_evidence | WBPerson1983 | |||||
| Sequence_name | ZK512.5 | ||||||||
| Molecular_name | ZK512.5a | ||||||||
| ZK512.5a.1 | |||||||||
| CE00411 | |||||||||
| ZK512.5b | |||||||||
| CE48211 | |||||||||
| ZK512.5b.1 | |||||||||
| Other_name | sec-16 | ||||||||
| CELE_ZK512.5 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | sec-16A.1 | ||||||||
| DB_info | Database | AceView | gene | 3K219 | |||||
| WormQTL | gene | WBGene00013985 | |||||||
| WormFlux | gene | WBGene00013985 | |||||||
| NDB | locus_tag | CELE_ZK512.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00013985|UniProtKB=P34643 | |||||||
| family | PTHR13402 | ||||||||
| NCBI | gene | 176289 | |||||||
| RefSeq | protein | NM_001306722.3 | |||||||
| NM_066621.5 | |||||||||
| SwissProt | UniProtAcc | P34643 | |||||||
| UniProt_GCRP | UniProtAcc | P34643 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 09 Jul 2010 16:38:16 | WBPerson2970 | Name_change | CGC_name | sec-16 | ||||
| 3 | 11 Sep 2019 12:48:59 | WBPerson1983 | Name_change | CGC_name | sec-16A.1 | ||||
| Other_name | sec-16 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sec | ||||||||
| Allele (61) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (45) | |||||||||
| Paralog | WBGene00017419 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00013985 | Caenorhabditis elegans | From_analysis | Inparanoid_8 | ||||||
| Structured_description | Concise_description | sec-16 encodes a scaffolding protein homologous to human SEC-16A (OMIM: 612854); SEC-16 directly interacts with TFG-1; SEC-16 localizes to endoplasmic reticulum exit sites with both TFG-1 and COPII machinery; levels of SEC-16 correlates with those of TFG-1, regardless of whether they were high or low SEC-16 requires TFG-1 to accumulate normally and TFG-1 requires SEC-16 for its localization on endoplasmic reticulum exit sites; normal assembly of large complexes containing SEC-16 and COPII subunits is facilitated by TFG-1 hexamers; SEC-16 on endoplasmic reticulum exit sites can continue to recruit COPII components in the absence of TFG-1, although to lower levels; Sec16 interacts with the N terminus of TFG in an evolutionarily conserved manner. SEC-16 is detectable at the two-cell stage of embryogenesis and expression continues throughout embryogenesis, punctated pattern in cytoplasm colocalizing with mitochondrial COX1. | Paper_evidence | WBPaper00038310 | |||||
| Curator_confirmed | WBPerson12884 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 20 Jul 2011 00:00:00 | ||||||||
| Automated_description | Involved in endoplasmic reticulum to Golgi vesicle-mediated transport and protein localization to endoplasmic reticulum exit site. Located in endoplasmic reticulum exit site. Is an ortholog of human SEC16A (SEC16 homolog A, endoplasmic reticulum export factor). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | ZK512.5a | |||||||
| ZK512.5b | |||||||||
| Corresponding_transcript | ZK512.5a.1 | ||||||||
| ZK512.5b.1 | |||||||||
| Other_sequence (26) | |||||||||
| Associated_feature | WBsf658530 | ||||||||
| WBsf659391 | |||||||||
| WBsf659392 | |||||||||
| WBsf993580 | |||||||||
| WBsf1015549 | |||||||||
| WBsf225525 | |||||||||
| WBsf225526 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00059474 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00038319 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092418 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00002609 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00059475 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00022039 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092403 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092411 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00085616 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00002800 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1013790 | ||||||||
| Expr1036252 | |||||||||
| Expr1162897 | |||||||||
| Expr2015710 | |||||||||
| Expr2033942 | |||||||||
| Drives_construct | WBCnstr00029394 | ||||||||
| Construct_product | WBCnstr00029394 | ||||||||
| Antibody | WBAntibody00002223 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (93) | |||||||||
| SAGE_tag (16) | |||||||||
| Interaction (50) | |||||||||
| Map_info | Map | III | Position | 0.169146 | Error | 0.001524 | |||
| Positive | Positive_clone | ZK512 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038310 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00042578 | |||||||||
| WBPaper00050531 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061547 | |||||||||
| WBPaper00062332 | |||||||||
| WBPaper00064057 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
