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WormBase Tree Display for Gene: WBGene00014020

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Name Class

WBGene00014020SMapS_parentSequenceZK632
IdentityVersion1
NameSequence_nameZK632.14
Molecular_nameZK632.14
ZK632.14.1
CE35163
Other_nameCELE_ZK632.14Accession_evidenceNDBBX284603
Public_nameZK632.14
DB_infoDatabaseAceViewgene3K903
WormQTLgeneWBGene00014020
WormFluxgeneWBGene00014020
NDBlocus_tagCELE_ZK632.14
PanthergeneCAEEL|WormBase=WBGene00014020|UniProtKB=Q7YWL9
familyPTHR13516
NCBIgene259525
RefSeqproteinNM_001027842.4
TREEFAMTREEFAM_IDTF325688
TrEMBLUniProtAccQ7YWL9
UniProt_GCRPUniProtAccQ7YWL9
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:55WBPerson1971EventImportedInitial conversion from CDS class of WS125
StatusLive
Gene_infoBiotypeSO:0001217
AlleleWBVar00852692
WBVar00852693
WBVar00852694
WBVar00852695
WBVar01500260
WBVar01499774
WBVar01952532
WBVar01567214
WBVar01567215
WBVar01701791
RNASeq_FPKM (74)
GO_annotation00082620
00082621
00082622
00082623
00120756
Contained_in_operonCEOP3881
Ortholog (31)
Structured_descriptionConcise_descriptionZK632.14 encodes an ortholog of Rpp25, a protein subunit shared by theendoribonucleases RNase MRP and RNAse P; RNAse MRP cleavesmitochondrial RNA in mitochondrial DNA synthesis, nucleolar pre-rRNA inribosome synthesis, and at least one mRNA (CLB2) involved in cell-cycleregulation; RNAse P cleaves tRNA precursors to produce their mature 5'end; ZK632.14 may dissociate from the RNase MRP complex when it bindsto ribosomal precursors.Paper_evidenceWBPaper00028606
WBPaper00028843
WBPaper00028845
WBPaper00028925
Curator_confirmedWBPerson567
Date_last_updated06 Jan 2007 00:00:00
Automated_descriptionPredicted to enable RNA binding activity. Predicted to be involved in tRNA 5'-leader removal. Predicted to be part of ribonuclease MRP complex. Human ortholog(s) of this gene implicated in autistic disorder. Is an ortholog of human RPP25 (ribonuclease P and MRP subunit p25) and RPP25L (ribonuclease P/MRP subunit p25 like).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:12849Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:30361)
Molecular_infoCorresponding_CDSZK632.14
Corresponding_transcriptZK632.14.1
Other_sequenceCJC02079_1
Associated_featureWBsf645521
WBsf993808
WBsf1015675
WBsf225632
Experimental_infoExpr_patternExpr1016980
Expr1036270
Expr1162987
Expr2008899
Expr2027133
Drives_constructWBCnstr00029373
Construct_productWBCnstr00029373
Microarray_results (13)
Expression_cluster (52)
Map_infoPositivePositive_cloneZK632Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionIII1.09135
ReferenceWBPaper00038491
WBPaper00055090
MethodGene