WormBase Tree Display for Gene: WBGene00014095
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WBGene00014095 | SMap | S_parent | Sequence | ZK829 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | gdh | ||||||
Allele (37) | |||||||
Strain | WBStrain00001547 | ||||||
WBStrain00002442 | |||||||
WBStrain00055460 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00079104 | ||||||
00079105 | |||||||
00079106 | |||||||
00079107 | |||||||
00079108 | |||||||
00079109 | |||||||
00120823 | |||||||
00120824 | |||||||
00120825 | |||||||
Ortholog (46) | |||||||
Paralog | WBGene00045131 | Caenorhabditis elegans | From_analysis | modENCODE_Pseudogenes | |||
Structured_description | Concise_description | gdh-1 encodes a glutamate dehydrogenase, required in mass RNAi assays for normal fertility and rapid growth, that is expressed in larval and adult pharynx, intestine, and rectal gland cells; GDH-1 is orthologous to human GLUD1 (OMIM:138130, mutated in hyperinsulinemic hypoglycemia and hyperammonemia) and GLUD2 (OMIM:300144). | Paper_evidence | WBPaper00006525 | |||
WBPaper00024497 | |||||||
WBPaper00029258 | |||||||
WBPaper00031006 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson1823 | |||||||
WBPerson567 | |||||||
Date_last_updated | 20 Sep 2011 00:00:00 | ||||||
Automated_description | Predicted to enable glutamate dehydrogenase (NAD+) activity. Predicted to be involved in glutamate catabolic process. Predicted to be located in mitochondrion. Expressed in head; intestine; pharynx; rectal gland cell; and tail. Human ortholog(s) of this gene implicated in Alzheimer's disease; glucose metabolism disease (multiple); and late onset Parkinson's disease. Is an ortholog of human GLUD1 (glutamate dehydrogenase 1). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:10652 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4335) | ||
DOID:9993 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4335) | ||||
DOID:0070217 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4335) | ||||
DOID:2018 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4335) | ||||
Molecular_info | Corresponding_CDS | ZK829.4 | |||||
Corresponding_transcript | ZK829.4.1 | ||||||
ZK829.4.2 | |||||||
Other_sequence (403) | |||||||
Associated_feature (13) | |||||||
Experimental_info | RNAi_result (17) | ||||||
Expr_pattern | Chronogram204 | ||||||
Expr7259 | |||||||
Expr7260 | |||||||
Expr14639 | |||||||
Expr1013000 | |||||||
Expr1036313 | |||||||
Expr1163175 | |||||||
Expr2012006 | |||||||
Expr2030242 | |||||||
Drives_construct | WBCnstr00002389 | ||||||
WBCnstr00029313 | |||||||
WBCnstr00041190 | |||||||
Construct_product | WBCnstr00016475 | ||||||
WBCnstr00029313 | |||||||
WBCnstr00041190 | |||||||
Microarray_results (26) | |||||||
Expression_cluster (222) | |||||||
Interaction (153) | |||||||
Map_info | Map | IV | Position | 5.45243 | Error | 0.000619 | |
Positive | Positive_clone | ZK829 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00033090 | ||||||
WBPaper00038491 | |||||||
WBPaper00041022 | |||||||
WBPaper00042178 | |||||||
WBPaper00049595 | |||||||
WBPaper00055090 | |||||||
WBPaper00059575 | |||||||
WBPaper00061178 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |