WormBase Tree Display for Gene: WBGene00015551
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WBGene00015551 | SMap | S_parent | Sequence | C06G3 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | adah-1 | Person_evidence | WBPerson7239 | |||
WBPerson3965 | |||||||
Sequence_name | C06G3.5 | ||||||
Molecular_name | C06G3.5a | ||||||
C06G3.5a.1 | |||||||
CE26867 | |||||||
C06G3.5b | |||||||
CE07981 | |||||||
C06G3.5b.1 | |||||||
C06G3.5b.2 | |||||||
Other_name | CELE_C06G3.5 | Accession_evidence | NDB | BX284604 | |||
Public_name | adah-1 | ||||||
DB_info | Database (13) | ||||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | adah | ||||||
Allele (35) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00021662 | ||||||
00021663 | |||||||
00021664 | |||||||
00021665 | |||||||
00021666 | |||||||
00021667 | |||||||
00021668 | |||||||
00021669 | |||||||
00121423 | |||||||
Ortholog (43) | |||||||
Paralog | WBGene00016632 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Panther | |||||||
WormBase-Compara | |||||||
Structured_description | Concise_description | C06G3.5 is orthologous to human ADENOSINE DEAMINASE (ADA; OMIM:102700), which when mutated leads to severe combined immunodeficiency; in C. elegans, C06G3.5 is an essential gene; C06G3.5 is broadly expressed; about 2% to 6% of C06G3.5a transcripts are RNA edited to change A to G resulting in a change to residue 59 from a D to a G. | Paper_evidence | WBPaper00045975 | |||
WBPaper00025054 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson1823 | |||||||
WBPerson4025 | |||||||
WBPerson567 | |||||||
Date_last_updated | 28 Dec 2014 00:00:00 | ||||||
Automated_description | Predicted to enable adenosine deaminase activity. Predicted to be involved in negative regulation of adenosine receptor signaling pathway and purine-containing compound metabolic process. Predicted to be located in cytosol and external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Legionnaires' disease; gastrointestinal system cancer (multiple); and lung disease (multiple). Is an ortholog of human ADA (adenosine deaminase). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model (22) | ||||||
Molecular_info | Corresponding_CDS | C06G3.5a | |||||
C06G3.5b | |||||||
Corresponding_transcript | C06G3.5a.1 | ||||||
C06G3.5b.1 | |||||||
C06G3.5b.2 | |||||||
Other_sequence (44) | |||||||
Associated_feature | WBsf646059 | ||||||
WBsf655028 | |||||||
WBsf996869 | |||||||
WBsf996870 | |||||||
WBsf1017641 | |||||||
WBsf228489 | |||||||
WBsf228490 | |||||||
Experimental_info | RNAi_result | WBRNAi00010341 | Inferred_automatically | RNAi_primary | |||
WBRNAi00028594 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00039937 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr5192 | ||||||
Expr1014251 | |||||||
Expr1036659 | |||||||
Expr1144011 | |||||||
Expr2000543 | |||||||
Expr2018769 | |||||||
Drives_construct | WBCnstr00003971 | ||||||
WBCnstr00028758 | |||||||
Construct_product | WBCnstr00028758 | ||||||
Microarray_results (26) | |||||||
Expression_cluster (200) | |||||||
Interaction (179) | |||||||
Map_info | Map | IV | Position | 3.27757 | |||
Positive | Positive_clone | C06G3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00038491 | ||||||
WBPaper00041771 | |||||||
WBPaper00055090 | |||||||
WBPaper00062899 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |