WormBase Tree Display for Gene: WBGene00016944
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| WBGene00016944 | SMap | S_parent | Sequence | C55B7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | uri-1 | Paper_evidence | WBPaper00027032 | |||||
| Person_evidence | WBPerson3787 | ||||||||
| WBPerson212 | |||||||||
| WBPerson4541 | |||||||||
| Sequence_name | C55B7.5 | ||||||||
| Molecular_name | C55B7.5 | ||||||||
| C55B7.5.1 | |||||||||
| CE09016 | |||||||||
| Other_name | CELE_C55B7.5 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | uri-1 | ||||||||
| DB_info | Database | AceView | gene | 1H71 | |||||
| WormQTL | gene | WBGene00016944 | |||||||
| WormFlux | gene | WBGene00016944 | |||||||
| NDB | locus_tag | CELE_C55B7.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00016944|UniProtKB=Q966M4 | |||||||
| family | PTHR15111 | ||||||||
| NCBI | gene | 183841 | |||||||
| RefSeq | protein | NM_059469.9 | |||||||
| TREEFAM | TREEFAM_ID | TF318785 | |||||||
| TrEMBL | UniProtAcc | Q966M4 | |||||||
| UniProt_GCRP | UniProtAcc | Q966M4 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:58 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 02 Feb 2006 09:28:57 | WBPerson2970 | Name_change | CGC_name | uri-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | uri | ||||||||
| Allele (24) | |||||||||
| Strain | WBStrain00007580 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (15) | |||||||||
| Structured_description | Concise_description | uri-1 encodes a molecular chaperone orthologous to the unconventional prefoldin RPB5 (RNA polymerase subunit 5) interactor, URI; in C.elegans, URI-1 activity is required for suppressing endogenous genotoxic DNA damage and thus, is essential for maintenance of genome integrity (DNA stability) and progression through the mitotic and meiotic cell cycles, particularly during germ cell development; URI-1 activity is also required for development of some somatic structures, such as the vulva, and for RNA interference; uri-1 mRNA is germline-enriched. | Paper_evidence | WBPaper00026593 | |||||
| WBPaper00027032 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 02 Aug 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable chromatin binding activity; phosphatase inhibitor activity; and transcription corepressor activity. Involved in several processes, including germ-line stem cell division; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; and regulation of cell cycle. Expressed in germ line. Is an ortholog of human URI1 (URI1 prefoldin like chaperone). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C55B7.5 | |||||||
| Corresponding_transcript | C55B7.5.1 | ||||||||
| Other_sequence | MIC01036_1 | ||||||||
| MI04249 | |||||||||
| Associated_feature | WBsf643372 | ||||||||
| WBsf654793 | |||||||||
| WBsf217834 | |||||||||
| WBsf217835 | |||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern | Expr3816 | ||||||||
| Expr1022828 | |||||||||
| Expr1037270 | |||||||||
| Expr1147210 | |||||||||
| Expr2017929 | |||||||||
| Expr2036065 | |||||||||
| Drives_construct | WBCnstr00027687 | ||||||||
| Construct_product | WBCnstr00027687 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (127) | |||||||||
| Interaction (124) | |||||||||
| Map_info | Map | I | Position | 1.16155 | Error | 0.001152 | |||
| Positive | Positive_clone | C55B7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00025876 | ||||||||
| WBPaper00026593 | |||||||||
| WBPaper00027032 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
