WormBase Tree Display for Gene: WBGene00017552

WBGene00017552 SMap: S_parent: Sequence: F18A12
  Identity: Version: 3
    Name: CGC_name: nep-7 Person_evidence: WBPerson260
      Sequence_name: F18A12.3
      Molecular_name: F18A12.3
      Other_name: CELE_F18A12.3 Accession_evidence: NDB BX284602
      Public_name: nep-7
    DB_info: Database: AceView gene 2D699
        WormQTL gene WBGene00017552
        WormFlux gene WBGene00017552
        NDB locus_tag CELE_F18A12.3
        NCBI gene 184630
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:59 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 10 Feb 2012 15:49:10 WBPerson2970 Name_change: CGC_name: nep-7
        3 21 Oct 2019 15:28:36 WBPerson4025 Event: Changed_class: CDS Pseudogene
    Status: Live
  Gene_info: Biotype: SO:0000336
    Gene_class: nep
    Allele (129)
    RNASeq_FPKM (74)
    Ortholog: WBGene00139354 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00164822 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00162313 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00152932 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00156516 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00191058 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00067444 Caenorhabditis remanei From_analysis: TreeFam
      WBGene00067447 Caenorhabditis remanei From_analysis: TreeFam
    Paralog (20)
    Structured_description: Concise_description: F18A12.3 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.3 has no clear orthologs in other organisms. Paper_evidence: WBPaper00004584
            WBPaper00013276
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enriched in male based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and eat-2 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including hydrogen sulfide; Tunicamycin; and multi-walled carbon nanotube based on microarray and RNA-seq studies. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS_history: F18A12.3:wp107
      F18A12.3:wp274
    Corresponding_pseudogene: F18A12.3
    Other_sequence: CJC04302_1
    Associated_feature: WBsf1011893
  Experimental_info: Expr_pattern: Expr1020652
      Expr1148890
    Drives_construct: WBCnstr00027212
    Construct_product: WBCnstr00027212
    Microarray_results (15)
    Expression_cluster (68)
    Interaction (32)
  Map_info: Map: II Position: -6.31146
    Positive: Positive_clone: F18A12 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00065080
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene