WormBase Tree Display for Gene: WBGene00017625
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WBGene00017625 | SMap | S_parent | Sequence | F20B4 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | cgt-2 | Person_evidence | WBPerson365 | |||||
Sequence_name | F20B4.6 | ||||||||
Molecular_name | F20B4.6 | ||||||||
F20B4.6.1 | |||||||||
CE30960 | |||||||||
F20B4.6.2 | |||||||||
Other_name | CELE_F20B4.6 | Accession_evidence | NDB | BX284606 | |||||
Public_name | cgt-2 | ||||||||
DB_info | Database (12) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:30:59 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 17 Mar 2006 15:11:54 | WBPerson2970 | Name_change | CGC_name | cgt-2 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | cgt | ||||||||
Allele (97) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (15) | |||||||||
Ortholog (38) | |||||||||
Paralog | WBGene00011517 | Caenorhabditis elegans | From_analysis | Panther | |||||
WormBase-Compara | |||||||||
WBGene00011519 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WBGene00019127 | Caenorhabditis elegans | From_analysis | Panther | ||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | cgt-2 encodes a transmembrane protein that is one of three C. elegans ceramide glucosyltransferases; by homology, CGT-2 is predicted to localize to the Golgi membrane and catalyze the transfer of glucose from UDP-glucose to ceramide to synthesize glucosylceramide, a glycosphingolipid precursor; although cgt-2 mutant worms show no obvious defects, cgt-3;cgt-1;cgt-2 triply mutant animals show reduced glucosylceramide levels; expression of cgt-2 in Saccharomyces cerevisiae results in de novo biosynthesis of glucosylceramides, absent from the parental strain. | Paper_evidence | WBPaper00032934 | |||||
WBPaper00035299 | |||||||||
WBPaper00035300 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 14 Oct 2009 00:00:00 | ||||||||
Automated_description | Predicted to enable ceramide glucosyltransferase activity. Predicted to be involved in glucosylceramide biosynthetic process. Predicted to be located in membrane. Expressed in intestine and vulva. Is an ortholog of human UGCG (UDP-glucose ceramide glucosyltransferase). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F20B4.6 | |||||||
Corresponding_transcript | F20B4.6.1 | ||||||||
F20B4.6.2 | |||||||||
Other_sequence | TS01900 | ||||||||
CBC08230_1 | |||||||||
CJC07754_1 | |||||||||
Associated_feature | WBsf1008999 | ||||||||
WBsf1009000 | |||||||||
WBsf1009001 | |||||||||
WBsf1009002 | |||||||||
WBsf1009003 | |||||||||
WBsf1025088 | |||||||||
WBsf1025089 | |||||||||
WBsf1025090 | |||||||||
Experimental_info | RNAi_result | WBRNAi00083996 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00045074 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00065439 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00013596 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00115312 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00116029 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00031156 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00083976 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr11538 | ||||||||
Expr1025700 | |||||||||
Expr1149025 | |||||||||
Expr2009947 | |||||||||
Expr2028187 | |||||||||
Drives_construct | WBCnstr00019064 | ||||||||
WBCnstr00027151 | |||||||||
Construct_product | WBCnstr00019064 | ||||||||
WBCnstr00027151 | |||||||||
Microarray_results (16) | |||||||||
Expression_cluster (108) | |||||||||
Interaction (12) | |||||||||
Map_info | Map | X | Position | 24.6168 | |||||
Positive | Positive_clone | F20B4 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (13) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |