Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00017625

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00017625SMapS_parentSequenceF20B4
IdentityVersion2
NameCGC_namecgt-2Person_evidenceWBPerson365
Sequence_nameF20B4.6
Molecular_nameF20B4.6
F20B4.6.1
CE30960
F20B4.6.2
Other_nameCELE_F20B4.6Accession_evidenceNDBBX284606
Public_namecgt-2
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:59WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
217 Mar 2006 15:11:54WBPerson2970Name_changeCGC_namecgt-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcgt
Allele (97)
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (38)
ParalogWBGene00011517Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00011519Caenorhabditis elegansFrom_analysisPanther
WBGene00019127Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptioncgt-2 encodes a transmembrane protein that is one of three C. elegans ceramide glucosyltransferases; by homology, CGT-2 is predicted to localize to the Golgi membrane and catalyze the transfer of glucose from UDP-glucose to ceramide to synthesize glucosylceramide, a glycosphingolipid precursor; although cgt-2 mutant worms show no obvious defects, cgt-3;cgt-1;cgt-2 triply mutant animals show reduced glucosylceramide levels; expression of cgt-2 in Saccharomyces cerevisiae results in de novo biosynthesis of glucosylceramides, absent from the parental strain.Paper_evidenceWBPaper00032934
WBPaper00035299
WBPaper00035300
Curator_confirmedWBPerson1843
Date_last_updated14 Oct 2009 00:00:00
Automated_descriptionPredicted to enable ceramide glucosyltransferase activity. Predicted to be involved in glucosylceramide biosynthetic process. Predicted to be located in membrane. Expressed in intestine and vulva. Is an ortholog of human UGCG (UDP-glucose ceramide glucosyltransferase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF20B4.6
Corresponding_transcriptF20B4.6.1
F20B4.6.2
Other_sequenceTS01900
CBC08230_1
CJC07754_1
Associated_featureWBsf1008999
WBsf1009000
WBsf1009001
WBsf1009002
WBsf1009003
WBsf1025088
WBsf1025089
WBsf1025090
Experimental_infoRNAi_resultWBRNAi00083996Inferred_automaticallyRNAi_primary
WBRNAi00045074Inferred_automaticallyRNAi_primary
WBRNAi00065439Inferred_automaticallyRNAi_primary
WBRNAi00013596Inferred_automaticallyRNAi_primary
WBRNAi00115312Inferred_automaticallyRNAi_primary
WBRNAi00116029Inferred_automaticallyRNAi_primary
WBRNAi00031156Inferred_automaticallyRNAi_primary
WBRNAi00083976Inferred_automaticallyRNAi_primary
Expr_patternExpr11538
Expr1025700
Expr1149025
Expr2009947
Expr2028187
Drives_constructWBCnstr00019064
WBCnstr00027151
Construct_productWBCnstr00019064
WBCnstr00027151
Microarray_results (16)
Expression_cluster (108)
Interaction (12)
Map_infoMapXPosition24.6168
PositivePositive_cloneF20B4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (13)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene