WormBase Tree Display for Gene: WBGene00018072

WBGene00018072 SMap: S_parent: Sequence: F35H10
  Identity: Version: 2
    Name: CGC_name: nprl-3 Person_evidence: WBPerson237
      Sequence_name: F35H10.7
      Molecular_name: F35H10.7a
        F35H10.7a.1
        CE04507
        F35H10.7b
        CE49655
        F35H10.7b.1
      Other_name: CELE_F35H10.7 Accession_evidence: NDB BX284604
      Public_name: nprl-3
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:59 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 11 Apr 2012 13:49:30 WBPerson2970 Name_change: CGC_name: nprl-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: nprl
    Allele (40)
    Strain: WBStrain00026538
      WBStrain00055427
    RNASeq_FPKM (74)
    GO_annotation (12)
    Contained_in_operon: CEOP4280
    Ortholog (34)
    Structured_description: Automated_description: Predicted to be involved in several processes, including TORC1 signaling; cellular response to amino acid starvation; and negative regulation of TORC1 signaling. Predicted to be located in lysosomal membrane. Predicted to be part of GATOR1 complex. Human ortholog(s) of this gene implicated in focal epilepsy. Is an ortholog of human NPRL3 (NPR3 like, GATOR1 complex subunit). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:2234 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:14124)
  Molecular_info: Corresponding_CDS: F35H10.7a
      F35H10.7b
    Corresponding_transcript: F35H10.7a.1
      F35H10.7b.1
    Other_sequence (23)
    Associated_feature: WBsf659798
      WBsf228656
  Experimental_info: RNAi_result: WBRNAi00008056 Inferred_automatically: RNAi_primary
      WBRNAi00014378 Inferred_automatically: RNAi_primary
      WBRNAi00046422 Inferred_automatically: RNAi_primary
      WBRNAi00076378 Inferred_automatically: RNAi_primary
      WBRNAi00014379 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr11031
      Expr1011015
      Expr1037786
      Expr1150290
      Expr2014431
      Expr2032672
    Drives_construct: WBCnstr00017863
      WBCnstr00026798
    Construct_product: WBCnstr00026798
    Microarray_results (24)
    Expression_cluster (106)
    SAGE_tag: SAGE:tgcttcatca Strand: Antisense
      SAGE:cttcattttttgtacat Strand: Antisense
      SAGE:accaaactga Strand: Antisense
      SAGE:cttcattttt Strand: Antisense
      SAGE:tcgaattctg Strand: Antisense
      SAGE:atcattcgacacttact Strand: Sense
        Unambiguously_mapped
      SAGE:agcatttgat Strand: Antisense
      SAGE:attttacccc Strand: Sense
        Unambiguously_mapped
      SAGE:aaaacttcaa Strand: Antisense
      SAGE:ctccaaaactattttgg Strand: Sense
        Unambiguously_mapped
    Interaction (35)
  Map_info: Map: IV Position: 3.7059
    Positive: Positive_clone: F35H10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00042436
    WBPaper00047025
    WBPaper00048330
    WBPaper00055090
    WBPaper00061997
    WBPaper00064064
    WBPaper00064505
    WBPaper00064506
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene