WormBase Tree Display for Gene: WBGene00018156
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| WBGene00018156 | SMap | S_parent | Sequence | F37E3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | ncbp-1 | |||||||
| Sequence_name | F37E3.1 | ||||||||
| Molecular_name | F37E3.1 | ||||||||
| F37E3.1.1 | |||||||||
| CE29793 | |||||||||
| Other_name | let-608 | ||||||||
| CELE_F37E3.1 | Accession_evidence | NDB | BX284601 | ||||||
| Public_name | ncbp-1 | ||||||||
| DB_info | Database | AceView | gene | 1H1 | |||||
| WormQTL | gene | WBGene00018156 | |||||||
| WormFlux | gene | WBGene00018156 | |||||||
| NDB | locus_tag | CELE_F37E3.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00018156|UniProtKB=O01763 | |||||||
| family | PTHR12412 | ||||||||
| NCBI | gene | 172345 | |||||||
| RefSeq | protein | NM_059449.7 | |||||||
| SwissProt | UniProtAcc | O01763 | |||||||
| TREEFAM | TREEFAM_ID | TF313400 | |||||||
| UniProt_GCRP | UniProtAcc | O01763 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:59 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 08 Jun 2007 15:14:26 | WBPerson2970 | Name_change | CGC_name | ncbp-1 | ||||
| 3 | 05 Mar 2015 11:26:57 | WBPerson2970 | Event | Acquires_merge | WBGene00002784 | ||||
| Name_change | Other_name | let-608 | |||||||
| Acquires_merge | WBGene00002784 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ncbp | ||||||||
| Allele (44) | |||||||||
| Legacy_information | [McDowall JS] Early larval arrest, lives 1-2 weeks | ||||||||
| [C.elegansII] h706 : early larval arrest, lives 1-2 weeks. OA2. [KR] | |||||||||
| Strain | WBStrain00023851 | ||||||||
| WBStrain00037146 | |||||||||
| In_cluster | conserved_miRNA_siRNA_cluster | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (38) | |||||||||
| Structured_description | Concise_description | ncbp-1 encodes a putative nuclear cap-binding complex subunit ('CBP80') orthologous to budding yeast STO1 and human NCBP1 (OMIM:600469); in RNAi assays, ncbp-1 is required for embryonic and vulval development, normal locomotion, and general viability; by orthology to NCBP1, NCBP-1 is expected to participate in nonsense-mediated mRNA decay via a pioneerround of translation; ncbp-1(RNAi) induces expression of a gpdh-1::GFP transgene, perhaps because NCBP-1 prevents protein misfolding. | Paper_evidence | WBPaper00006395 | |||||
| WBPaper00024497 | |||||||||
| WBPaper00026846 | |||||||||
| WBPaper00028383 | |||||||||
| WBPaper00029269 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 20 Apr 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable RNA cap binding activity and mRNA binding activity. Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to be located in nucleus. Predicted to be part of mRNA cap binding activity complex and nuclear cap binding activity complex. Is an ortholog of human NCBP1 (nuclear cap binding protein subunit 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F37E3.1 | |||||||
| Corresponding_transcript | F37E3.1.1 | ||||||||
| Other_sequence (14) | |||||||||
| Associated_feature | WBsf643367 | ||||||||
| WBsf217821 | |||||||||
| WBsf217822 | |||||||||
| Experimental_info | RNAi_result (29) | ||||||||
| Expr_pattern | Expr1017505 | ||||||||
| Expr1037821 | |||||||||
| Expr1150515 | |||||||||
| Expr2013903 | |||||||||
| Expr2032143 | |||||||||
| Drives_construct | WBCnstr00026738 | ||||||||
| Construct_product | WBCnstr00017523 | ||||||||
| WBCnstr00026738 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (138) | |||||||||
| Interaction (267) | |||||||||
| WBProcess | WBbiopr:00000081 | ||||||||
| Map_info | Map | I | Position | 1.08274 | Error | 0.002296 | |||
| Well_ordered | |||||||||
| Positive | Positive_clone | F37E3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Negative | Negative_clone | C29F10 | |||||||
| K04F10 | |||||||||
| Mapping_data | Pos_neg_data (11) | ||||||||
| Pseudo_map_position | |||||||||
| Reference (13) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| [McDowall JS] Extrachromosomal array containing two cosmids generated, then manipulated genetically. | |||||||||
| Method | Gene |
