WormBase Tree Display for Gene: WBGene00018330
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| WBGene00018330 | SMap | S_parent | Sequence | F42A6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | elks-1 | Person_evidence | WBPerson451 | |||||
| Sequence_name | F42A6.9 | ||||||||
| Molecular_name | F42A6.9 | ||||||||
| F42A6.9.1 | |||||||||
| CE28392 | |||||||||
| Other_name | CELE_F42A6.9 | Accession_evidence | NDB | BX284604 | |||||
| Public_name | elks-1 | ||||||||
| DB_info | Database | AceView | gene | 4E108 | |||||
| WormQTL | gene | WBGene00018330 | |||||||
| WormFlux | gene | WBGene00018330 | |||||||
| NDB | locus_tag | CELE_F42A6.9 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00018330|UniProtKB=O44490 | |||||||
| family | PTHR18861 | ||||||||
| NCBI | gene | 177102 | |||||||
| RefSeq | protein | NM_067928.5 | |||||||
| TREEFAM | TREEFAM_ID | TF324969 | |||||||
| TrEMBL | UniProtAcc | O44490 | |||||||
| UniProt_GCRP | UniProtAcc | O44490 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 25 Jan 2005 16:28:46 | WBPerson2970 | Name_change | CGC_name | elks-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | elks | ||||||||
| Allele (144) | |||||||||
| Strain | WBStrain00029066 | ||||||||
| WBStrain00029068 | |||||||||
| WBStrain00037303 | |||||||||
| WBStrain00052562 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (14) | |||||||||
| Ortholog (39) | |||||||||
| Structured_description | Concise_description | elks-1 encodes the C. elegans homolog of the vertebrate ELKS (glutamine, leucine, lysine, and serine-rich) proteins; although loss of elks-1 activity results in no obvious developmental or behavioral abnormalities, the ELKS-1 C-terminus interacts with the PDZ domain of UNC-10/RIM in vitro, and in vivo each protein appears to play a nonessential role in localizing the other to the presynaptic active zone; in addition to the active zone, ELKS-1 also localizes to the pharyngeal basal lamina. | Paper_evidence | WBPaper00026618 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 25 Oct 2006 00:00:00 | ||||||||
| Automated_description | Enables PDZ domain binding activity. Involved in protein localization and regulation of protein deneddylation. Located in basement membrane and presynaptic active zone. Expressed in nervous system. Is an ortholog of human ERC2 (ELKS/RAB6-interacting/CAST family member 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F42A6.9 | |||||||
| Corresponding_transcript | F42A6.9.1 | ||||||||
| Other_sequence (39) | |||||||||
| Associated_feature (11) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00047069 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00002391 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00014804 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00033487 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr4960 | ||||||||
| Expr4968 | |||||||||
| Expr12357 | |||||||||
| Expr1015636 | |||||||||
| Expr1037894 | |||||||||
| Expr1150933 | |||||||||
| Expr2011275 | |||||||||
| Expr2029511 | |||||||||
| Construct_product | WBCnstr00006778 | ||||||||
| WBCnstr00012369 | |||||||||
| WBCnstr00012377 | |||||||||
| WBCnstr00018352 | |||||||||
| WBCnstr00018386 | |||||||||
| WBCnstr00018967 | |||||||||
| WBCnstr00022488 | |||||||||
| WBCnstr00042067 | |||||||||
| Regulate_expr_cluster | WBPaper00061818:ELKS-1_interacting | ||||||||
| Antibody | WBAntibody00001019 | ||||||||
| WBAntibody00001020 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (124) | |||||||||
| Interaction (1277) | |||||||||
| Map_info | Map | IV | Position | -4.60667 | Error | 0.02445 | |||
| Positive | Positive_clone | F42A6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5073 | |||||||
| 4414 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (18) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
