WormBase Tree Display for Gene: WBGene00018672
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| WBGene00018672 | SMap | S_parent | Sequence | F52C9 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | sorf-2 | Paper_evidence | WBPaper00049116 | |||||
| Person_evidence | WBPerson2241 | ||||||||
| Sequence_name | F52C9.1 | ||||||||
| Molecular_name | F52C9.1 | ||||||||
| F52C9.1.1 | |||||||||
| CE54107 | |||||||||
| Other_name | wdr-81 | ||||||||
| CELE_F52C9.1 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | sorf-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 19 Feb 2016 12:45:33 | WBPerson2970 | Name_change | CGC_name | sorf-2 | ||||
| 3 | 19 Jan 2016 15:53:33 | WBPerson2970 | Name_change | Other_name | wdr-81 | ||||
| Acquires_merge | WBGene00018673 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sorf | ||||||||
| Allele (87) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (25) | |||||||||
| Contained_in_operon | CEOP3284 | ||||||||
| Ortholog (30) | |||||||||
| Paralog | WBGene00004760 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00007752 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00011361 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | wdr-81 encodes a BEACH-WD40 domain-containing protein; loss of wdr-81 activity results in low levels of aldicarb resistance, suggesting that wdr-81 may play a role in synapse structure and function. | Paper_evidence | WBPaper00026667 | |||||
| WBPaper00028987 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 19 Jan 2016 00:00:00 | ||||||||
| Automated_description | Predicted to enable phosphatidylinositol 3-kinase inhibitor activity. Involved in organelle fusion and positive regulation of early endosome to late endosome transport. Located in early endosome and late endosome. Human ortholog(s) of this gene implicated in cerebellar ataxia, mental retardation and dysequlibrium syndrome and hydrocephalus. Is an ortholog of human WDR81 (WD repeat domain 81). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0050997 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:26600) | ||||
| DOID:10908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:26600) | ||||||
| Molecular_info | Corresponding_CDS | F52C9.1 | |||||||
| Corresponding_CDS_history | F52C9.1:wp275 | ||||||||
| F52C9.1a:wp88 | |||||||||
| F52C9.1a:wp146 | |||||||||
| F52C9.1a:wp186 | |||||||||
| F52C9.1a:wp214 | |||||||||
| F52C9.1b:wp146 | |||||||||
| F52C9.1b:wp186 | |||||||||
| F52C9.1b:wp214 | |||||||||
| Corresponding_transcript | F52C9.1.1 | ||||||||
| Other_sequence (22) | |||||||||
| Associated_feature | WBsf658938 | ||||||||
| WBsf992359 | |||||||||
| WBsf992360 | |||||||||
| WBsf1014869 | |||||||||
| WBsf1014870 | |||||||||
| Experimental_info | RNAi_result (16) | ||||||||
| Expr_pattern | Expr12702 | ||||||||
| Expr1019938 | |||||||||
| Expr1038036 | |||||||||
| Expr1151772 | |||||||||
| Expr2016011 | |||||||||
| Expr2034246 | |||||||||
| Construct_product | WBCnstr00022458 | ||||||||
| WBCnstr00022460 | |||||||||
| Microarray_results (32) | |||||||||
| Expression_cluster (103) | |||||||||
| Interaction | WBInteraction000007547 | ||||||||
| WBInteraction000007617 | |||||||||
| WBInteraction000256659 | |||||||||
| WBInteraction000327689 | |||||||||
| WBInteraction000413171 | |||||||||
| WBInteraction000542253 | |||||||||
| WBInteraction000542256 | |||||||||
| Map_info | Map | III | Position | -1.81902 | |||||
| Positive | Positive_clone | F52C9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00049116 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00061184 | |||||||||
| WBPaper00063815 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
