WormBase Tree Display for Gene: WBGene00018974
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WBGene00018974 | SMap | S_parent | Sequence | F56D12 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | fcho-1 | Person_evidence | WBPerson3188 | |||||
Sequence_name | F56D12.6 | ||||||||
Molecular_name | F56D12.6a | ||||||||
F56D12.6a.1 | |||||||||
CE23782 | |||||||||
F56D12.6b | |||||||||
CE11256 | |||||||||
F56D12.6b.1 | |||||||||
Other_name | CELE_F56D12.6 | Accession_evidence | NDB | BX284602 | |||||
Public_name | fcho-1 | ||||||||
DB_info | Database (11) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:01 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 08 Aug 2013 16:41:57 | WBPerson2970 | Name_change | CGC_name | fcho-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | fcho | ||||||||
Allele (195) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00021831 | ||||||||
00021832 | |||||||||
00021833 | |||||||||
00021834 | |||||||||
00021835 | |||||||||
00021836 | |||||||||
00021837 | |||||||||
00097251 | |||||||||
00097252 | |||||||||
Ortholog (48) | |||||||||
Paralog | WBGene00018467 | Caenorhabditis elegans | From_analysis | Panther | |||||
Structured_description | Concise_description | fcho-1 encodes the sole C. elegans homolog of the F-BAR domain-containing Fer/Cip4 homology domain-only (FCHo) family of proteins; FCHO-1 functions as an endocytic adaptor protein to regulate cargo sorting through the endolysosomal system; immunofluorescence staining of embryos indicates that FCHO-1 localizes to the plasma membrane. | Paper_evidence | WBPaper00042550 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 19 Sep 2013 00:00:00 | ||||||||
Automated_description | Involved in clathrin-dependent endocytosis. Located in plasma membrane. Expressed in amphid neurons; hypodermis; intestine; pharyngeal cell; and rectal gland cell. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is an ortholog of human FCHO2 (FCH and mu domain containing endocytic adaptor 2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:29002) | ||||
Molecular_info | Corresponding_CDS | F56D12.6a | |||||||
F56D12.6b | |||||||||
Corresponding_CDS_history | F56D12.6:wp15 | ||||||||
Corresponding_transcript | F56D12.6a.1 | ||||||||
F56D12.6b.1 | |||||||||
Other_sequence (12) | |||||||||
Associated_feature | WBsf643955 | ||||||||
WBsf643956 | |||||||||
WBsf657329 | |||||||||
WBsf986648 | |||||||||
WBsf986649 | |||||||||
WBsf986650 | |||||||||
WBsf1011532 | |||||||||
WBsf220833 | |||||||||
WBsf220834 | |||||||||
Experimental_info | RNAi_result | WBRNAi00048694 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00061983 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00098485 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00062525 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00032955 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr11309 | ||||||||
Expr1028968 | |||||||||
Expr1038190 | |||||||||
Expr1152449 | |||||||||
Expr2011744 | |||||||||
Expr2029982 | |||||||||
Drives_construct | WBCnstr00018759 | ||||||||
Construct_product | WBCnstr00019780 | ||||||||
WBCnstr00019781 | |||||||||
WBCnstr00019790 | |||||||||
WBCnstr00019791 | |||||||||
WBCnstr00019792 | |||||||||
WBCnstr00019793 | |||||||||
Antibody | WBAntibody00002464 | ||||||||
Microarray_results (28) | |||||||||
Expression_cluster (91) | |||||||||
Interaction | WBInteraction000032370 | ||||||||
WBInteraction000169154 | |||||||||
WBInteraction000271965 | |||||||||
WBInteraction000304992 | |||||||||
WBInteraction000393523 | |||||||||
WBInteraction000463347 | |||||||||
WBInteraction000548305 | |||||||||
WBInteraction000554046 | |||||||||
WBInteraction000565593 | |||||||||
WBInteraction000572700 | |||||||||
Map_info | Map | II | Position | -15.5017 | |||||
Positive | Positive_clone | F56D12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00038491 | ||||||||
WBPaper00042550 | |||||||||
WBPaper00045908 | |||||||||
WBPaper00047378 | |||||||||
WBPaper00049789 | |||||||||
WBPaper00051874 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00057834 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |